Joseph Bellal, Jokar Tahereh O, Khalil Mazhar, Haider Ansab A, Kulvatunyou Narong, Zangbar Bardiya, Tang Andrew, Zeeshan Muhammad, O'Keeffe Terence, Abbas Daniyal, Latifi Rifat, Rhee Peter
Division of Trauma, Critical Care, Emergency Surgery, and Burns, Department of Surgery, University of Arizona, Tucson, AZ, USA.
Division of Trauma, Critical Care, Emergency Surgery, and Burns, Department of Surgery, University of Arizona, Tucson, AZ, USA.
Am J Surg. 2016 Jun;211(6):982-8. doi: 10.1016/j.amjsurg.2015.10.027. Epub 2016 Jan 7.
Blunt cardiac injury (BCI) is an infrequent but potentially fatal finding in thoracic trauma. Its clinical presentation is highly variable and patient characteristics and injury pattern have never been described in trauma patients. The aim of this study was to identify predictors of mortality in BCI patients.
We performed an 8-year retrospective analysis of all trauma patients diagnosed with BCI at our Level 1 trauma center. Patients older than 18 years, blunt chest trauma, and a suspected diagnosis of BCI were included. BCI was diagnosed based on the presence of electrocardiography (EKG), echocardiography, biochemical cardiac markers, and/or radionuclide imaging studies. Elevated troponin I was defined as more than 2 recordings of greater than or equal to .2. Abnormal EKG findings were defined as the presence of bundle branch block, ST segment, and t-wave abnormalities. Univariate and multivariate regression analyses were performed.
A total of 117 patients with BCI were identified. The mean age was 51 ± 22 years, 65% were male, mean systolic blood pressure was 93 ± 65, and overall mortality rate was 44%. Patients who died were more likely to have a lactate greater than 2.5 (68% vs 31%, P = .02), hypotension (systolic blood pressure < 90) (86% vs 14%, P = .001), and elevated troponin I (86% vs 11%, P = .01). There was no difference in the rib fracture (58% vs 56%, P = .8), sternal fracture (11% vs 21%, P = .2), and abnormal EKG (89% vs 90%, P = .6) findings. Hypotension and lactate greater than 2.5 were the strongest predictors of mortality in BCI.
BCI remains an important diagnostic and management challenge. However, once diagnosed resuscitative therapy focused on correction of hypotension and lactate may prove beneficial. Although the role of troponin in diagnosing BCI remains controversial, elevated troponin may have prognostic significance.
钝性心脏损伤(BCI)在胸部创伤中虽不常见但可能致命。其临床表现高度多变,创伤患者的患者特征和损伤模式从未被描述过。本研究的目的是确定BCI患者的死亡预测因素。
我们对在我们的一级创伤中心诊断为BCI的所有创伤患者进行了为期8年的回顾性分析。纳入年龄大于18岁、钝性胸部创伤且疑似诊断为BCI的患者。BCI根据心电图(EKG)、超声心动图、生化心脏标志物和/或放射性核素成像研究进行诊断。肌钙蛋白I升高定义为大于或等于0.2的记录有2次以上。异常EKG表现定义为存在束支传导阻滞、ST段和T波异常。进行了单因素和多因素回归分析。
共识别出117例BCI患者。平均年龄为51±22岁,65%为男性,平均收缩压为93±65,总死亡率为44%。死亡患者更可能乳酸水平大于2.5(68%对31%,P = 0.02)、低血压(收缩压<90)(86%对14%,P = 0.001)和肌钙蛋白I升高(86%对11%,P = 0.01)。肋骨骨折(58%对56%,P = 0.8)、胸骨骨折(11%对21%,P = 0.2)和异常EKG(89%对90%,P = 0.6)表现无差异。低血压和乳酸水平大于2.5是BCI患者死亡的最强预测因素。
BCI仍然是一个重要的诊断和管理挑战。然而,一旦诊断,专注于纠正低血压和乳酸的复苏治疗可能被证明是有益的。尽管肌钙蛋白在诊断BCI中的作用仍存在争议,但肌钙蛋白升高可能具有预后意义。