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Steroids are part of rescue therapy in ARDS patients with refractory hypoxemia: we are not sure.对于难治性低氧血症的急性呼吸窘迫综合征患者，类固醇是挽救治疗的一部分：我们并不确定。
Intensive Care Med. 2016 May;42(5):924-927. doi: 10.1007/s00134-015-4160-z. Epub 2016 Jan 29.
2
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3
Steroids are part of rescue therapy in ARDS patients with refractory hypoxemia: yes.对于难治性低氧血症的急性呼吸窘迫综合征（ARDS）患者，类固醇是抢救治疗的一部分：是。
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[Acute respiratory distress syndrome. Role of steroids].
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[Acute respiratory distress syndrome].[急性呼吸窘迫综合征]
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Dexamethasone fails to improve bleomycin-induced acute lung injury in mice.地塞米松未能改善博来霉素诱导的小鼠急性肺损伤。
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Beyond Low Tidal Volume Ventilation: Treatment Adjuncts for Severe Respiratory Failure in Acute Respiratory Distress Syndrome.超越低潮气量通气：急性呼吸窘迫综合征严重呼吸衰竭的治疗辅助手段。
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本文引用的文献

1
Prolonged glucocorticoid treatment is associated with improved ARDS outcomes: analysis of individual patients' data from four randomized trials and trial-level meta-analysis of the updated literature.长期糖皮质激素治疗与改善 ARDS 结局相关：四项随机试验的个体患者数据分析和更新文献的试验水平荟萃分析。
Intensive Care Med. 2016 May;42(5):829-840. doi: 10.1007/s00134-015-4095-4. Epub 2015 Oct 27.
2
Adjunctive corticosteroids for Pneumocystis jiroveci pneumonia in patients with HIV infection.艾滋病病毒感染患者耶氏肺孢子菌肺炎的辅助性皮质类固醇治疗
Cochrane Database Syst Rev. 2015 Apr 2;2015(4):CD006150. doi: 10.1002/14651858.CD006150.pub2.
3
Type III procollagen is a reliable marker of ARDS-associated lung fibroproliferation.III 型前胶原是 ARDS 相关肺纤维化增殖的可靠标志物。
Intensive Care Med. 2015 Jan;41(1):1-11. doi: 10.1007/s00134-014-3524-0. Epub 2014 Oct 30.
4
Exploring the heterogeneity of effects of corticosteroids on acute respiratory distress syndrome: a systematic review and meta-analysis.探索皮质类固醇对急性呼吸窘迫综合征影响的异质性：一项系统评价和荟萃分析。
Crit Care. 2014 Apr 7;18(2):R63. doi: 10.1186/cc13819.
5
Chronology of histological lesions in acute respiratory distress syndrome with diffuse alveolar damage: a prospective cohort study of clinical autopsies.急性呼吸窘迫综合征伴弥漫性肺泡损伤的组织学病变时间进程：临床尸检的前瞻性队列研究。
Lancet Respir Med. 2013 Jul;1(5):395-401. doi: 10.1016/S2213-2600(13)70053-5. Epub 2013 May 15.
6
ARDS: progress unlikely with non-biological definition.急性呼吸窘迫综合征：采用非生物学定义时进展可能性不大。
Br J Anaesth. 2013 Nov;111(5):696-9. doi: 10.1093/bja/aet165.
7
A new definition for the acute respiratory distress syndrome.急性呼吸窘迫综合征的新定义。
Semin Respir Crit Care Med. 2013 Aug;34(4):441-7. doi: 10.1055/s-0033-1351162. Epub 2013 Aug 11.
8
Corticosteroid use in the intensive care unit: a survey of intensivists.皮质类固醇在重症监护病房中的应用：对重症监护医师的调查。
Can J Anaesth. 2013 Jul;60(7):652-9. doi: 10.1007/s12630-013-9929-3. Epub 2013 Apr 19.
9
Comparison of the Berlin definition for acute respiratory distress syndrome with autopsy.柏林急性呼吸窘迫综合征定义与尸检比较。
Am J Respir Crit Care Med. 2013 Apr 1;187(7):761-7. doi: 10.1164/rccm.201211-1981OC.
10
Acute respiratory distress syndrome: the Berlin Definition.急性呼吸窘迫综合征：柏林定义。
JAMA. 2012 Jun 20;307(23):2526-33. doi: 10.1001/jama.2012.5669.

Steroids are part of rescue therapy in ARDS patients with refractory hypoxemia: we are not sure.

作者信息

Seam Nitin, Suffredini Anthony F

机构信息

Critical Care Medicine Department, Clinical Center, National Institutes of Health, Building 10, Room 2C145, 10 Center Drive, Bethesda, MD, 20892-1662, USA.

出版信息

Intensive Care Med. 2016 May;42(5):924-927. doi: 10.1007/s00134-015-4160-z. Epub 2016 Jan 29.

DOI:10.1007/s00134-015-4160-z
PMID:26883255
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5554951/
Abstract
摘要