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肥胖对急性全身性炎症期间的发热和疾病行为有影响。

Obesity Impacts Fever and Sickness Behavior During Acute Systemic Inflammation.

机构信息

Department of Veterinary-Physiology and Biochemistry, Justus-Liebig-University Giessen, Giessen, Germany; and

Department of Veterinary-Physiology and Biochemistry, Justus-Liebig-University Giessen, Giessen, Germany; and.

出版信息

Physiology (Bethesda). 2016 Mar;31(2):117-30. doi: 10.1152/physiol.00049.2015.

DOI:10.1152/physiol.00049.2015
PMID:26889017
Abstract

Obesity is reaching dramatic proportions in humans and is associated with a higher risk for cardiovascular disease, diabetes, and cognitive alterations, and a higher mortality during infection and inflammation. The focus of the present review is on the influence of obesity on the presentation of fever, sickness behavior, and inflammatory responses during acute systemic inflammation.

摘要

肥胖症在人类中达到了惊人的程度，与心血管疾病、糖尿病和认知改变的风险增加以及感染和炎症期间的死亡率增加有关。本综述的重点是肥胖对急性全身炎症期间发热、疾病行为和炎症反应表现的影响。

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