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Perioperative complications after live-donor hepatectomy.活体肝移植术后的围手术期并发症。
JAMA Surg. 2014 Mar;149(3):288-91. doi: 10.1001/jamasurg.2013.3835.
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Cancer statistics, 2014.癌症统计数据,2014 年。
CA Cancer J Clin. 2014 Jan-Feb;64(1):9-29. doi: 10.3322/caac.21208. Epub 2014 Jan 7.
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Prevalence of obesity among adults: United States, 2011-2012.2011 - 2012年美国成年人肥胖患病率
NCHS Data Brief. 2013 Oct(131):1-8.
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Periprostatic fat area is an independent factor that prolonged operative time in laparoscopic radical prostatectomy.前列腺周围脂肪区是腹腔镜前列腺根治术手术时间延长的独立因素。
Urology. 2013 Dec;82(6):1304-9. doi: 10.1016/j.urology.2013.04.077. Epub 2013 Sep 21.
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Population-based determinants of radical prostatectomy operative time.基于人群的前列腺根治术手术时间决定因素。
BJU Int. 2014 May;113(5b):E112-8. doi: 10.1111/bju.12451. Epub 2014 Jan 15.
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The cost of obesity for nonbariatric inpatient operative procedures in the United States: national cost estimates obese versus nonobese patients.美国非减肥手术住院患者肥胖相关成本:肥胖与非肥胖患者的国家成本估计。
Ann Surg. 2013 Oct;258(4):541-51; discussion 551-3. doi: 10.1097/SLA.0b013e3182a500ce.
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Obese men have more advanced and more aggressive prostate cancer at time of surgery than non-obese men after adjusting for screening PSA level and age: results from two independent nested case-control studies.肥胖男性在接受手术时的前列腺癌比非肥胖男性更为晚期和侵袭性,这种差异在调整了筛查 PSA 水平和年龄后仍然存在:来自两项独立的巢式病例对照研究的结果。
Prostate Cancer Prostatic Dis. 2013 Dec;16(4):352-6. doi: 10.1038/pcan.2013.27. Epub 2013 Aug 20.
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National obesity trends in total knee arthroplasty.全国范围内全膝关节置换术肥胖趋势。
J Arthroplasty. 2013 Sep;28(8 Suppl):148-51. doi: 10.1016/j.arth.2013.02.036. Epub 2013 Aug 15.
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Laparoscopic and robotic radical prostatectomy outcomes in obese and extremely obese men.腹腔镜和机器人根治性前列腺切除术在肥胖和极度肥胖男性中的疗效。
Urology. 2013 Sep;82(3):600-5. doi: 10.1016/j.urology.2013.05.013. Epub 2013 Jul 13.
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Role of abdominal obesity for functional outcomes and complications in men treated with radical prostatectomy for prostate cancer: results of the Multicenter Italian Report on Radical Prostatectomy (MIRROR) study.腹型肥胖在接受前列腺癌根治术的男性患者功能结局及并发症中的作用:多中心意大利前列腺癌根治术报告(MIRROR)研究结果
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肥胖男性行开放性与机器人辅助根治性前列腺切除术的比较

Open Versus Robotic Radical Prostatectomy in Obese Men.

作者信息

Ellimoottil Chandy, Roghmann Florian, Blackwell Robert, Kadlec Adam, Greco Kristin, Quek Marcus L, Sun Maxine, Trinh Quoc-Dien, Gupta Gopal

机构信息

Loyola University Medical Center, Maywood, IL., USA.

Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Canada; Department of Urology, Ruhr University Bochum, Marienhospital, Herne, Germany.

出版信息

Curr Urol. 2015 Sep;8(3):156-61. doi: 10.1159/000365708. Epub 2015 Sep 4.

DOI:10.1159/000365708
PMID:26889136
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4748755/
Abstract

OBJECTIVES

Robotic-assisted radical prostatectomy (RARP) has been shown to reduce blood loss, peri-operative complications and length of stay when compared to open radical prostatectomy (ORP). We sought to determine whether the reported benefits of RARP over ORP translate to obese patients.

PATIENTS AND METHODS

We utilized the 2009-2010 Nationwide Inpatient Sample to identify all obese men with prostate cancer who underwent ORP and RARP. Our primary outcome was the presence of a peri-operative adverse event (i.e. blood transfusion, complication, prolonged length of stay). We fit multivariable logistic regression models to examine whether RARP in obese patients was independently associated with decreased odds of all three outcomes.

RESULTS

We identified 9,108 obese patients who underwent radical prostatectomy. On multivariable analysis, the use of RARP in the obese population was not independently associated with decreased odds of developing a peri-operative complication (OR = 0.81, CI: 0.58-1.13, p = 0.209). RARP was, however, associated with decreased odds of blood transfusion (OR = 0.17, CI: 0.10-0.30, p < 0.001) and prolonged length of stay (OR = 0.28, CI: 0.20-0.40, p < 0.001).

CONCLUSION

Our findings suggest that in obese patients, the use of RARP may reduce length of stay and blood transfusions compared to ORP. Both approaches, however, are associated with similar odds of developing a complication.

摘要

目的

与开放性根治性前列腺切除术(ORP)相比,机器人辅助根治性前列腺切除术(RARP)已被证明可减少失血、围手术期并发症及住院时间。我们试图确定RARP相对于ORP所报告的益处是否适用于肥胖患者。

患者与方法

我们利用2009 - 2010年全国住院患者样本,识别所有接受ORP和RARP的肥胖前列腺癌男性患者。我们的主要结局是围手术期不良事件的发生情况(即输血、并发症、住院时间延长)。我们拟合多变量逻辑回归模型,以检验肥胖患者接受RARP是否与这三种结局发生几率降低独立相关。

结果

我们识别出9108例接受根治性前列腺切除术的肥胖患者。多变量分析显示,肥胖人群中使用RARP与围手术期并发症发生几率降低无独立相关性(OR = 0.81,CI:0.58 - 1.13,p = 0.209)。然而,RARP与输血几率降低(OR = 0.17,CI:0.10 - 0.30,p < 0.001)及住院时间延长几率降低(OR = 0.28,CI:0.20 - 0.40,p < 0.001)相关。

结论

我们的研究结果表明,在肥胖患者中,与ORP相比,使用RARP可能会减少住院时间和输血情况。然而,两种手术方式发生并发症的几率相似。