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慢性胆囊炎中罕见的胆囊纤毛前肠囊肿。

A rare gallbladder ciliated foregut cyst in chronic cholecystitis.

作者信息

Lee Mee-Jin, Salinas James, Varikatthas Winny, Alsnih Ghiyath

机构信息

Department of General Surgery, Blacktown Hospital, Sydney, New South Wales, Australia.

Department of General Surgery, Blacktown Hospital, Sydney, New South Wales, Australia.

出版信息

Int J Surg Case Rep. 2016;20:155-8. doi: 10.1016/j.ijscr.2016.01.023. Epub 2016 Jan 22.

Abstract

INTRODUCTION

Ciliated foregut cysts (CFC) are rare anomalies due to aberrant embryological development. It is thought to arise from a remnant of the embryologic foregut. The solitary cysts are characterised by ciliated pseudostratified columnar epithelium. They are usually located above the diaphragm but they can also arise in relation to the liver, gallbladder and pancreas.

PRESENTATION OF CASE

We present the first ciliated foregut cyst of the gallbladder case reported in Australia, and the ninth known case to be reported worldwide. A 61-year-old male with chronic cholecystitis and cholelithiasis underwent an elective laparoscopic cholecystectomy and intraoperative cholangiogram. Intraoperatively, 'out-pouching' was noted on the lateral border of the gallbladder. Microscopically the histopathology showed that the cyst was lined by ciliated columnar epithelium the characteristic feature of a ciliated foregut cyst.

DISCUSSION

To date only 8 cases of these ciliated foregut cysts in the gallbladder have been reported in literature. Our case is the first reported in Australia. It is unique in that the patient was an older male as opposed to most other previous cases, which were younger females. These cysts can be difficult to distinguish from neoplasms clinically and radiographically. Reports have shown that these cysts may become dysplastic and is best excised when discovered.

CONCLUSION

Despite the rarity of CFCs and their potential to mimic malignancy, we propose awareness and understanding of the management for them-being excision and hopefully not cause any confusion or devastatingly allow it to become malignant.

摘要

引言

纤毛前肠囊肿(CFC)是由于胚胎发育异常而导致的罕见畸形。它被认为起源于胚胎前肠的残余部分。孤立性囊肿的特征是有纤毛的假复层柱状上皮。它们通常位于膈肌上方,但也可发生于肝脏、胆囊和胰腺相关部位。

病例介绍

我们报告了澳大利亚首例胆囊纤毛前肠囊肿病例,也是全球第九例已知报告病例。一名患有慢性胆囊炎和胆结石的61岁男性接受了择期腹腔镜胆囊切除术及术中胆管造影。术中,在胆囊外侧缘发现“袋状突出”。显微镜下组织病理学显示囊肿内衬有纤毛柱状上皮,这是纤毛前肠囊肿的特征性表现。

讨论

迄今为止,文献中仅报道了8例胆囊纤毛前肠囊肿病例。我们的病例是澳大利亚首例报告病例。其独特之处在于患者为老年男性,而大多数先前病例为年轻女性。这些囊肿在临床和影像学上可能难以与肿瘤区分。报告显示这些囊肿可能会发育异常,发现时最好切除。

结论

尽管纤毛前肠囊肿罕见且有潜在的恶性模仿可能,但我们建议提高对其治疗方法的认识和理解——即切除,希望不会引起任何混淆或令人痛心的是任其恶变。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0735/4818304/eacd4e16120a/gr1.jpg

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