平阳霉素局部注射治疗睑黄瘤
Treatment of Xanthelasma Palpebrarum With Intralesional Pingyangmycin.
作者信息
Wang Hui, Shi Yingshen, Guan Huapeng, Liu Caiyue, Zhang Wenjun, Zhang Yingfan, Liu Antang, Qian Yuxin, Zhao Yaozhong, Jiang Hua
机构信息
*Department of Plastic and Reconstructive Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, China; †Department of Orthopedics, PLA 456 Hospital, Jinan, China.
出版信息
Dermatol Surg. 2016 Mar;42(3):368-76. doi: 10.1097/DSS.0000000000000660.
BACKGROUND
Xanthelasma palpebrarum (xanthelasma) is the most common type of cutaneous xanthoma, and many patients tend to seek medical treatments for cosmetic reasons. Many methods treating xanthelasma have been proposed, but none of these options can be regarded as a perfect solution.
OBJECTIVE
To study and evaluate the intralesional injection treatment of xanthelasma with pingyangmycin, which has been widely used as a broad-spectrum antitumor antibiotic.
MATERIALS AND METHODS
21 lesions in 12 patients were treated by intralesional pingyangmycin. Photographs were taken before and after each treatment session. Patients were followed up for 7 to 36 months.
RESULTS
All patients except one received satisfactory results after up to 2 sessions. Only 1 patient had a local recurrence 1 year after the treatment. No severe complications such as infection, atrophy, ulceration, or scar were noticed.
CONCLUSION
Intralesional pingyangmycin is a cheap, effective, and safe treatment for xanthelasma, which has been well accepted by patients.
背景
睑黄瘤是最常见的皮肤型黄瘤，许多患者因美容原因倾向于寻求医学治疗。已经提出了许多治疗睑黄瘤的方法，但这些方法都不能被视为完美的解决方案。
目的
研究和评估用平阳霉素进行瘤内注射治疗睑黄瘤，平阳霉素已被广泛用作一种广谱抗肿瘤抗生素。
材料和方法
对12例患者的共21处病损进行平阳霉素瘤内注射治疗。每次治疗前后均拍照。患者随访7至36个月。
结果
除1例患者外，所有患者在最多2次治疗后均取得满意效果。仅1例患者在治疗1年后出现局部复发。未观察到感染、萎缩、溃疡或瘢痕等严重并发症。
结论
平阳霉素瘤内注射治疗睑黄瘤价廉、有效且安全，已被患者广泛接受。
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