State Key Laboratory of Heavy Oil Processing, China University of Petroleum, Beijing 102249, PR China.
State Key Laboratory of Heavy Oil Processing, China University of Petroleum, Beijing 102249, PR China; Department of Materials Science and Engineering, China University of Petroleum, Beijing 102249, PR China.
Biosens Bioelectron. 2016 Jun 15;80:511-518. doi: 10.1016/j.bios.2016.02.004. Epub 2016 Feb 3.
TiO2 modified Co3O4 acicular nanotube arrays (ANTAs) have been fabricated in this study, showing a good performance in glucose detection. In the experiment, the precursor Co(CO3)0.5(OH)·0.11H2O acicular nanowire arrays (ANWAs) was first grown on the fluorine doped tin oxide (FTO) substrate by a hydrothermal method. Thereafter, the uniform pink precursor Co(CO3)0.5(OH)·0.11H2O ANWAs was completely converted to the black Co3O4 ANTAs thin film by alkaline treatment. After the decoration of TiO2, the TiO2/Co3O4 ANTAs electrode exhibits a much higher current response to glucose compared with the Co3O4 ANTAs. Importantly, this neotype composite structure of Co3O4 enhances the glucose sensing performance by increasing specific surface area, additional reactive sites and synergistic effect, which make the TiO2/Co3O4 glucose sensor show a high sensitivity of 2008.82 μA mM(-1) cm(-2), a fast response time (less than 5s) and a detection limit as low as 0.3396 μM (S/N=3). The TiO2/Co3O4 ANTAs modified electrode exhibits a high selectivity for glucose in human serum, against ascorbic acid and uric acid.
本研究制备了 TiO2 修饰的 Co3O4 针状纳米管阵列（ANTAs），在葡萄糖检测中表现出良好的性能。在实验中，首先通过水热法在掺氟氧化锡（FTO）基底上生长出前驱体 Co(CO3)0.5(OH)·0.11H2O 针状纳米线阵列（ANWAs）。然后，通过碱性处理将均匀的粉红色前驱体 Co(CO3)0.5(OH)·0.11H2O ANWAs 完全转化为黑色 Co3O4 ANTAs 薄膜。TiO2 修饰后，TiO2/Co3O4 ANTAs 电极对葡萄糖的电流响应明显高于 Co3O4 ANTAs。重要的是，Co3O4 的这种新型复合结构通过增加比表面积、增加反应活性位点和协同作用，提高了葡萄糖传感性能，使 TiO2/Co3O4 葡萄糖传感器表现出 2008.82 μA mM(-1) cm(-2) 的高灵敏度、快速响应时间（<5s）和低检测限 0.3396 μM（S/N=3）。TiO2/Co3O4 ANTAs 修饰电极对人血清中的葡萄糖具有较高的选择性，对抗坏血酸和尿酸的干扰较小。
