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Laparoscopic versus open surgery for colorectal cancer in the older person: A systematic review.老年人结直肠癌的腹腔镜手术与开放手术:一项系统评价。
Ann Med Surg (Lond). 2015 Aug 12;4(3):311-8. doi: 10.1016/j.amsu.2015.08.002. eCollection 2015 Sep.
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Laparoscopic management of intra-abdominal infections: Systematic review of the literature.腹腔镜治疗腹腔内感染:文献系统评价
World J Gastrointest Surg. 2015 Aug 27;7(8):160-9. doi: 10.4240/wjgs.v7.i8.160.
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100 classic papers of interventional radiology: A citation analysis.介入放射学100篇经典论文:一项引文分析。
World J Radiol. 2015 Apr 28;7(4):79-86. doi: 10.4329/wjr.v7.i4.79.
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Risk prediction models for postoperative delirium: a systematic review and meta-analysis.术后谵妄的风险预测模型:一项系统评价与荟萃分析
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Prevalence of frailty and its association with mortality in general surgery.普通外科中衰弱的患病率及其与死亡率的关联。
Am J Surg. 2015 Feb;209(2):254-9. doi: 10.1016/j.amjsurg.2014.05.022. Epub 2014 Jul 27.
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The prevalence of cognitive impairment in emergency general surgery.急危重症外科认知障碍的发生率。
Int J Surg. 2014 Oct;12(10):1031-5. doi: 10.1016/j.ijsu.2014.07.020. Epub 2014 Aug 14.
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Physical rehabilitation for older people in long-term care.长期护理机构中老年人的身体康复
Cochrane Database Syst Rev. 2013 Feb 28;2013(2):CD004294. doi: 10.1002/14651858.CD004294.pub3.
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Frailty in elderly people.老年人虚弱。
Lancet. 2013 Mar 2;381(9868):752-62. doi: 10.1016/S0140-6736(12)62167-9. Epub 2013 Feb 8.
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Cognitive trajectories after postoperative delirium.术后谵妄后的认知轨迹。
N Engl J Med. 2012 Jul 5;367(1):30-9. doi: 10.1056/NEJMoa1112923.
10
Are the frail destined to fail? Frailty index as predictor of surgical morbidity and mortality in the elderly.虚弱的人注定会失败吗?虚弱指数预测老年人的手术发病率和死亡率。
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衰弱与认知障碍:老年急诊外科患者面临的独特挑战。

Frailty and cognitive impairment: Unique challenges in the older emergency surgical patient.

作者信息

Moug S J, Stechman M, McCarthy K, Pearce L, Myint P K, Hewitt J

机构信息

Royal Alexandra Hospital , Paisley , UK.

University Hospital of Wales , Cardiff , UK.

出版信息

Ann R Coll Surg Engl. 2016 Mar;98(3):165-9. doi: 10.1308/rcsann.2016.0087.

DOI:10.1308/rcsann.2016.0087
PMID:26890834
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5226174/
Abstract

INTRODUCTION

Older patients (>65 years of age) admitted as general surgical emergencies increasingly require improved recognition of their specific needs relative to younger patients. Two such needs are frailty and cognitive impairment. These are evolving research areas that the emergency surgeon increasingly requires knowledge of to improve short- and long-term patient outcomes.

METHODS

This paper reviews the evidence for frailty and cognitive impairment in the acute surgical setting by defining frailty and cognitive impairment, introducing methods of diagnosis, discussing the influence on prognosis and proposing strategies to improve older patient outcomes.

RESULTS

Frailty is present in 25% of the older surgical population. Using frailty-scoring tools, frailty was associated with a significantly longer hospital stay and higher mortality at 30 and 90 days after admission to an acute surgical unit. Cognitive impairment is present in a high number of older acute surgical patients (approximately 70%), whilst acute onset cognitive impairment, termed delirium, is documented in 18%. However, patients with delirium had significantly longer hospital stays and higher in-hospital mortality than those with cognitive impairment.

CONCLUSIONS

Improved knowledge of frailty and delirium by the emergency surgeon allows the specialised needs of older surgical patients to be taken into account. Early recognition, and consideration of minimally invasive surgery or radiological intervention alongside potentially transferable successful elective interventions such as comprehensive geriatric assessment, may help to improve short- and long-term patient outcomes in this vulnerable population.

摘要

引言

因普通外科急症入院的老年患者(>65岁)越来越需要针对其相对于年轻患者的特殊需求,提供更好的识别与应对措施。其中两项需求是衰弱和认知障碍。这些是不断发展的研究领域,急诊外科医生越来越需要了解这些领域,以改善患者的短期和长期预后。

方法

本文通过定义衰弱和认知障碍、介绍诊断方法、讨论对预后的影响并提出改善老年患者预后的策略,回顾了急性外科环境中衰弱和认知障碍的相关证据。

结果

25%的老年外科患者存在衰弱。使用衰弱评分工具,衰弱与急性外科病房入院后30天和90天显著更长的住院时间及更高的死亡率相关。大量老年急性外科患者存在认知障碍(约70%),而急性起病的认知障碍,即谵妄,记录在18%的患者中。然而,谵妄患者的住院时间明显长于认知障碍患者,且院内死亡率更高。

结论

急诊外科医生对衰弱和谵妄有更深入的了解,有助于考虑老年外科患者的特殊需求。早期识别,并考虑微创手术或放射介入,同时结合可能可推广的成功的择期干预措施,如综合老年评估,可能有助于改善这一脆弱人群患者的短期和长期预后。