• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Absence of immunosuppression in DBA/2 mice vaccinated with Trypanosoma cruzi treated with actinomycin-D.

作者信息

Queiroz da Cruz M, Bräscher H M, Vargens J R, Maia L C, Oliveira-Lima A

机构信息

Instituto de Puericultura e Pediatria de UFR, Rio de Janeiro, Brazil.

出版信息

Experientia. 1989 Dec 1;45(11-12):1131-3. doi: 10.1007/BF01950179.

DOI:10.1007/BF01950179
PMID:2689205
Abstract

The subcutaneous (s.c.) vaccination of DBA/2 mice with 4 weekly doses of 3 x 10(7) living metacyclic forms of T. cruzi, Y strain, obtained from culture in axenic medium and treated for 24 h with actinomycin-D (50 micrograms/10(7) parasites), a drug that promotes an irreversible blockade of the parasite replication, do not induce any detectable degree of humoral and cellular immunosuppression as assessed by a) the production of anti-SRBC antibodies, b) the permanence of delayed cutaneous reaction to T. cruzi antigen, to PPD and DNCB and c) the degree of blastogenic transformation of spleen lymphocytes in the presence of the specific antigen.

摘要

相似文献

1
Absence of immunosuppression in DBA/2 mice vaccinated with Trypanosoma cruzi treated with actinomycin-D.
Experientia. 1989 Dec 1;45(11-12):1131-3. doi: 10.1007/BF01950179.
2
Molecular basis of Trypanosoma cruzi-induced immunosuppression. Altered expression by activated human lymphocytes of molecules which regulate antigen recognition and progression through the cell cycle.克氏锥虫诱导免疫抑制的分子基础。活化的人类淋巴细胞对调节抗原识别及细胞周期进程的分子的表达改变。
Biol Res. 1993;26(1-2):197-207.
3
GP 50/55, a membrane antigen of Trypanosoma cruzi involved in autoimmunity and immunosuppression.GP 50/55，一种参与自身免疫和免疫抑制的克氏锥虫膜抗原。
Biol Res. 1993;26(1-2):209-18.
4
Immune suppression to Trypanosoma cruzi antigens is associated with infection but not immunisation.对克氏锥虫抗原的免疫抑制与感染有关，而非免疫接种。
Trop Med Parasitol. 1986 Jun;37(2):97-100.
5
A Trypanosoma cruzi membrane protein shares an epitope with a lymphocyte activation antigen and induces crossreactive antibodies.一种克氏锥虫膜蛋白与一种淋巴细胞激活抗原共享一个表位，并诱导交叉反应性抗体。
J Exp Med. 1992 Jun 1;175(6):1473-82. doi: 10.1084/jem.175.6.1473.
6
Inhibition of Trypanosoma cruzi-specific immune responses by a protein produced by T. cruzi in the course of Chagas' disease.克氏锥虫在恰加斯病病程中产生的一种蛋白质对克氏锥虫特异性免疫反应的抑制作用。
Immunology. 1994 Mar;81(3):462-7.
7
Experimental Chagas disease in Balb/c mice previously vaccinated with T. rangeli. II. The innate immune response shows immunological memory: reality or fiction?先前用克氏锥虫疫苗接种的Balb/c小鼠的实验性恰加斯病。II. 先天免疫反应显示免疫记忆：是现实还是虚构？
Immunobiology. 2015 Mar;220(3):428-36. doi: 10.1016/j.imbio.2014.10.003. Epub 2014 Oct 30.
8
[Immunological aspects of infection of 6 inbred strains of mice by 3 different strains of Trypanosoma cruzi].[3种不同克氏锥虫菌株感染6种近交系小鼠的免疫学方面]
Mem Inst Oswaldo Cruz. 1985 Apr-Jun;80(2):203-11. doi: 10.1590/s0074-02761985000200011.
9
A 24,000 MW Trypanosoma cruzi antigen is a B-cell activator.一种24000兆瓦的克氏锥虫抗原是一种B细胞激活剂。
Immunology. 1998 Jun;94(2):189-96. doi: 10.1046/j.1365-2567.1998.00498.x.
10
Suppression of polyclonal antibody production in Trypanosoma cruzi-infected mice by treatment with anti-L3T4 antibodies.
J Immunol. 1987 Jul 15;139(2):545-50.

本文引用的文献

1
On evasion of Trypanosoma cruzi from the host immune response. Lymphoproliferative responses to trypanosomal antigens during acute and chronic experimental Chagas' disease.关于克氏锥虫对宿主免疫反应的逃避。急性和慢性实验性恰加斯病期间对锥虫抗原的淋巴细胞增殖反应。
Immunology. 1981 Nov;44(3):641-8.
2
Trypanosoma cruzi-induced suppression of the primary immune response in murine cell cultures to T-cell-dependent and -independent antigens.克氏锥虫诱导鼠细胞培养物中对T细胞依赖性和非依赖性抗原的原发性免疫应答抑制。
J Parasitol. 1980 Feb;66(1):16-27.
3
Delayed hypersensitivity to Trypanosoma cruzi in mice: specific suppressor cells in chronic infection.
小鼠对克氏锥虫的迟发型超敏反应：慢性感染中的特异性抑制细胞。
Immunology. 1981 Oct;44(2):409-17.
4
Suppression of mouse lymphocyte responses to mitogens in vitro by Trypanosoma cruzi.克氏锥虫对体外培养的小鼠淋巴细胞有丝分裂原反应的抑制作用。
Int J Parasitol. 1984 Feb;14(1):45-52. doi: 10.1016/0020-7519(84)90010-9.
5
Novel mechanism for Trypanosoma cruzi-induced suppression of human lymphocytes. Inhibition of IL-2 receptor expression.克氏锥虫诱导人类淋巴细胞抑制的新机制。白细胞介素-2受体表达的抑制。
J Immunol. 1988 Jul 1;141(1):289-94.
6
Trypanosoma cruzi: early immune responses in infected mice.克氏锥虫：感染小鼠的早期免疫反应
Exp Parasitol. 1975 Jun;37(3):417-25. doi: 10.1016/0014-4894(75)90012-0.
7
Suppression of cell-mediated immunity in experimental Chagas' disease.
Z Parasitenkd. 1977 Jun 3;52(1):11-7. doi: 10.1007/BF00380553.
8
Suppressor cells present in the spleens of Trypanosoma cruzi-infected mice.克氏锥虫感染小鼠脾脏中存在的抑制细胞。
J Immunol. 1979 Apr;122(4):1243-7.
9
Suppression of humoral responses during Trypanosoma cruzi infections in mice.小鼠感染克氏锥虫期间体液免疫反应的抑制
Infect Immun. 1978 Oct;22(1):155-60. doi: 10.1128/iai.22.1.155-160.1978.