甲硝唑致肝脓肿患者神经毒性1例报告及MRI在其诊断中的应用价值
A Case Report of Metronidazole Induced Neurotoxicity in Liver Abscess Patient and the Usefulness of MRI for its Diagnosis.
作者信息
Chandak Shruti, Agarwal Arjit, Shukla Arvind, Joon Pawan
机构信息
Associate Professor, Department of Radiodiagnosis, Teerthanker Mahaveer Medical College , Moradabad, Uttar Pradesh, India .
Assistant Professor, Department of Radiodiagnosis, Teerthanker Mahaveer Medical College , Moradabad, Uttar Pradesh, India .
出版信息
J Clin Diagn Res. 2016 Jan;10(1):TD06-7. doi: 10.7860/JCDR/2016/14900.7031. Epub 2016 Jan 1.
Metronidazole is a very widely used drug for the treatment of multiple ailments caused by anaerobic bacteria as well as some protozoan parasites. Though its usual side effects are not very serious, yet sometimes it may cause profound adverse effects like neurotoxicity. We present here a case of liver abscess. The patient was treated for a long time with metronidazole and developed sudden onset neurotoxicity which was diagnosed by MRI. The present case also highlights the need of vigilant monitoring of patients on metronidazole for symptoms of neurotoxicity and the usefulness of MRI for diagnosis of the same.
甲硝唑是一种广泛用于治疗由厌氧菌以及某些原生动物寄生虫引起的多种疾病的药物。虽然其常见副作用不太严重，但有时可能会引起如神经毒性等严重不良反应。我们在此呈现一例肝脓肿病例。该患者长期使用甲硝唑治疗，突然出现神经毒性，经磁共振成像（MRI）诊断。本病例还强调了对使用甲硝唑的患者需密切监测神经毒性症状，以及MRI对诊断神经毒性的有用性。
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