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使用Agility机头和平坦滤过器自由模式对Versa HD直线加速器进行Pinnacle3建模和端到端剂量测定测试。

Pinnacle3 modeling and end-to-end dosimetric testing of a Versa HD linear accelerator with the Agility head and flattening filter-free modes.

作者信息

Saenz Daniel L, Narayanasamy Ganesh, Cruz Wilbert, Papanikolaou Nikos, Stathakis Sotirios

机构信息

University of Texas Health Science Center - San Antonio.

出版信息

J Appl Clin Med Phys. 2016 Jan 8;17(1):192-206. doi: 10.1120/jacmp.v17i1.5808.

Abstract

The Elekta Versa HD incorporates a variety of upgrades to the line of Elekta linear accelerators, primarily including the Agility head and flattening filter-free (FFF) photon beam delivery. The completely distinct dosimetric output of the head from its predecessors, combined with the FFF beams, requires a new investigation of modeling in treatment planning systems. A model was created in Pinnacle3 v9.8 with the commissioned beam data. A phantom consisting of several plastic water and Styrofoam slabs was scanned and imported into Pinnacle3, where beams of different field sizes, source-to-surface distances (SSDs), wedges, and gantry angles were devised. Beams included all of the available photon energies (6, 10, 18, 6FFF, and 10 FFF MV), as well as the four electron energies commissioned for clinical use (6, 9, 12, and 15 MeV). The plans were verified at calculation points by measurement with a calibrated ionization chamber. Homogeneous and hetero-geneous point-dose measurements agreed within 2% relative to maximum dose for all photon and electron beams. AP photon open field measurements along the central axis at 100 cm SSD passed within 1%. In addition, IMRT testing was also performed with three standard plans (step and shoot IMRT, as well as a small- and large-field VMAT plan). The IMRT plans were delivered on the Delta4 IMRT QA phantom, for which a gamma passing rate was > 99.5% for all plans with a 3% dose deviation, 3 mm distance-to-agreement, and 10% dose threshold. The IMRT QA results for the first 23 patients yielded gamma passing rates of 97.4% ± 2.3%. Such testing ensures confidence in the ability of Pinnacle3 to model photon and electron beams with the Agility head.

摘要

医科达Versa HD对医科达直线加速器系列进行了多种升级,主要包括Agility机头和无均整器(FFF)光子束传输。该机头与之前的型号相比,剂量输出完全不同,再结合FFF光束,需要在治疗计划系统中对建模进行新的研究。在Pinnacle3 v9.8中利用已调试的射束数据创建了一个模型。扫描了一个由几块塑料水模和聚苯乙烯泡沫塑料板组成的模体,并将其导入Pinnacle3,在其中设计了不同射野大小、源皮距(SSD)、楔形板和机架角度的射束。射束包括所有可用的光子能量(6、10、18、6FFF和10 FFF MV),以及调试用于临床的四种电子能量(6、9、12和15 MeV)。通过使用校准电离室进行测量,在计算点对计划进行了验证。所有光子和电子束的均匀和非均匀点剂量测量结果与最大剂量相比,在2%以内相符。在100 cm SSD处沿中心轴的前后光子开放野测量结果在1%以内通过。此外,还使用三个标准计划(静态调强放疗以及小场和大场容积调强弧形治疗计划)进行了调强放疗测试。调强放疗计划在Delta4调强放疗质量保证模体上实施,对于所有计划,在剂量偏差为3%、距离一致性为3 mm和剂量阈值为10%的情况下,伽马通过率>99.5%。前23例患者的调强放疗质量保证结果显示伽马通过率为97.4%±2.3%。此类测试确保了对Pinnacle3使用Agility机头对光子和电子束进行建模能力的信心。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adb6/5690210/9e0d2c4b46c7/ACM2-17-192-g001.jpg

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