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使用瓦里安 Eclipse 治疗计划系统对 Elekta VersaHD 进行光子束建模:单机构经验。

Modeling Elekta VersaHD using the Varian Eclipse treatment planning system for photon beams: A single-institution experience.

机构信息

UT Southwestern Medical Center, Dallas, TX, USA.

Roswell Park Cancer Institute, Buffalo, NK, USA.

出版信息

J Appl Clin Med Phys. 2019 Oct;20(10):33-42. doi: 10.1002/acm2.12709. Epub 2019 Aug 30.

Abstract

The aim of this study was to report a single-institution experience and commissioning data for Elekta VersaHD linear accelerators (LINACs) for photon beams in the Eclipse treatment planning system (TPS). Two VersaHD LINACs equipped with 160-leaf collimators were commissioned. For each energy, the percent-depth-dose (PDD) curves, beam profiles, output factors, leaf transmission factors and dosimetric leaf gaps (DLGs) were acquired in accordance with the AAPM task group reports No. 45 and No. 106 and the vendor-supplied documents. The measured data were imported into Eclipse TPS to build a VersaHD beam model. The model was validated by creating treatment plans spanning over the full-spectrum of treatment sites and techniques used in our clinic. The quality assurance measurements were performed using MatriXX, ionization chamber, and radiochromic film. The DLG values were iteratively adjusted to optimize the agreement between planned and measured doses. Mobius, an independent LINAC logfile-based quality assurance tool, was also commissioned both for routine intensity-modulated radiation therapy (IMRT) QA and as a secondary check for the Eclipse VersaHD model. The Eclipse-generated VersaHD model was in excellent agreement with the measured PDD curves and beam profiles. The measured leaf transmission factors were less than 0.5% for all energies. The model validation study yielded absolute point dose agreement between ionization chamber measurements and Eclipse within ±4% for all cases. The comparison between Mobius and Eclipse, and between Mobius and ionization chamber measurements lead to absolute point dose agreement within ±5%. The corresponding 3D dose distributions evaluated with 3%global/2mm gamma criteria resulted in larger than 90% passing rates for all plans. The Eclipse TPS can model VersaHD LINACs with clinically acceptable accuracy. The model validation study and comparisons with Mobius demonstrated that the modeling of VersaHD in Eclipse necessitates further improvement to provide dosimetric accuracy on par with Varian LINACs.

摘要

本研究旨在报告在 Eclipse 治疗计划系统(TPS)中使用 Elekta VersaHD 直线加速器(LINAC)进行光子束的单机构经验和委托数据。两台配备 160 叶准直器的 VersaHD LINAC 进行了委托。对于每个能量,根据 AAPM 工作组报告 No.45 和 No.106 以及供应商提供的文件,获取百分深度剂量(PDD)曲线、射束轮廓、输出因子、叶片传输因子和剂量学叶片间隙(DLG)。将测量数据导入 Eclipse TPS 以建立 VersaHD 射束模型。通过创建跨越我们诊所使用的治疗部位和技术的全谱治疗计划来验证模型。使用 MatriXX、电离室和光致变色胶片进行质量保证测量。通过迭代调整 DLG 值来优化计划剂量与测量剂量之间的一致性。还委托了独立的基于 LINAC 日志文件的质量保证工具 Mobius 进行常规调强放射治疗(IMRT)QA 以及作为 Eclipse VersaHD 模型的二级检查。Eclipse 生成的 VersaHD 模型与测量的 PDD 曲线和射束轮廓非常吻合。所有能量的叶片传输因子均小于 0.5%。对于所有情况,电离室测量值与 Eclipse 之间的绝对点剂量一致性在±4%以内。Mobius 与 Eclipse 之间以及 Mobius 与电离室测量值之间的比较导致绝对点剂量一致性在±5%以内。使用 3%全局/2mm 伽马标准评估的相应 3D 剂量分布所有计划的通过率均大于 90%。Eclipse TPS 可以以临床可接受的精度对 VersaHD LINAC 进行建模。模型验证研究和与 Mobius 的比较表明,在 Eclipse 中对 VersaHD 进行建模需要进一步改进,以提供与瓦里安 LINAC 相当的剂量学准确性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d90/6806469/9d31db15ef75/ACM2-20-33-g001.jpg

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