Wehr T A
Clinical Psychobiology Branch, National Institute of Mental Health, Bethesda, Md. 20892.
J Clin Psychiatry. 1989 Dec;50 Suppl:8-16; discussion 45-7.
Experiments show that sleep loss can trigger symptoms of mania or hypomania in certain bipolar patients. Exposure to light might have a similar effect in some patients with seasonal forms of bipolar illness. Attention to the possible role of sleep loss and light as triggering factors in the pathogenesis of mania may help clinicians and patients to identify some of the factors that influence the natural course of the bipolar illness and to devise strategies for its prevention and treatment.
实验表明，睡眠不足会在某些双相情感障碍患者中引发躁狂或轻躁狂症状。对于某些季节性双相情感障碍患者，暴露于光线之下可能会产生类似的效果。关注睡眠不足和光线作为躁狂症发病机制中的触发因素所可能起到的作用，或许有助于临床医生和患者识别一些影响双相情感障碍自然病程的因素，并制定预防和治疗策略。
