25秒内完成右心室成像：评估使用稀疏采样电影成像结合迭代重建技术对右心室进行容积分析的应用。
Right Ventricular Imaging in 25 Seconds: Evaluating the Use of Sparse Sampling CINE With Iterative Reconstruction for Volumetric Analysis of the Right Ventricle.
作者信息
Haubenreisser Holger, Henzler Thomas, Budjan Johannes, Sudarski Sonja, Zenge Michael O, Schmidt Michaela, Nadar Mariappan S, Borggrefe Martin, Schoenberg Stefan O, Papavassiliu Theano
机构信息
From the *Institute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University; †DZHK (German Centre for Cardiovascular Research) Partner Site, Mannheim; ‡MR Product Innovation and Definition, Healthcare Sector, Siemens AG, Erlangen, Germany; §Imaging and Computer Vision, Siemens AG, Corporate Technology, Princeton, NJ; and ∥First Department of Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
出版信息
Invest Radiol. 2016 Jun;51(6):379-86. doi: 10.1097/RLI.0000000000000250.
OBJECTIVE
The aim of this study was to prospectively evaluate a 2-dimensional real-time CINE TrueFISP magnetic resonance sequence using sparse data sampling with iterative reconstruction (SSIR) for right ventricular (RV) volumetry in comparison to the criterion standard (CS) acquired at 3 T.
MATERIALS AND METHODS
Ten healthy controls and 20 consecutive patients scheduled for cardiac magnetic resonance imaging on a 3-T system (Magnetom Skyra; Siemens Healthcare Sector, Germany) underwent undersampled SSIR sequences with a single breath-hold (BH) as well as with shallow free breathing (NBH) and a fully sampled multi-BH sequence as CS. Right ventricular volumetry was performed with dedicated cardiac magnetic resonance software (cvi42; Circle Cardiovascular Imaging Inc, Calgary, Alberta, Canada). Agreement of SSIR with and without BH and CS for RV functional parameters (end-systolic volume [RVESV], end-diastolic volume [RVEDV], stroke volume [RVSV], and ejection fraction [RVEF]) were assessed with Bland-Altman analysis and paired t test.
RESULTS
Analysis of the 30 individuals (19 male; 48 ± 14 years) revealed no significant differences when comparing CS and BH measurements for RVEDV (153.7 vs 153.6 mL, P = 0.96), RVESV (71.6 vs 72.1 mL, P = 0.78), RVSV (82.0 vs 81.6 mL, P = 0.65), and RVEF (54.9% vs 54.2%, P = 0.19). Similar results were shown when comparing CS and NBH measurements for RVEDV (153.7 vs 152.2 mL, P = 0.34), RVESV (71.6 vs 72.8 mL, P = 0.30), RVSV (82.0 vs 81.0 mL, P = 0.46), and RVEF (54.9 vs 54.4, P = 0.48). Time taken for acquisition was 350 seconds for the CS, 34 seconds for BH, and 25 seconds for NBH measurements. Additional time required for iterative reconstruction was 2 minutes and 30 seconds for the sparse sampled data sets.
CONCLUSIONS
Our results demonstrate that accurate RV volumetry with SSIR data at 3 T is feasible in clinical routine within 25 seconds even without BH, which is of particular importance in patients with dyspnea.
目的
本研究旨在前瞻性评估二维实时电影TrueFISP磁共振序列，该序列采用稀疏数据采样和迭代重建（SSIR）技术进行右心室（RV）容积测量，并与在3T场强下获取的标准参考值（CS）进行比较。
材料与方法
10名健康对照者和20名计划在3T系统（Magnetom Skyra；德国西门子医疗集团）上进行心脏磁共振成像的连续患者，接受了单次屏气（BH）和浅呼吸（非屏气，NBH）的欠采样SSIR序列，以及作为标准参考值的全采样多屏气序列。使用专用的心脏磁共振软件（cvi42；加拿大阿尔伯塔省卡尔加里市Circle心血管成像公司）进行右心室容积测量。采用Bland-Altman分析和配对t检验评估有屏气和无屏气的SSIR与标准参考值在右心室功能参数（收缩末期容积[RVESV]、舒张末期容积[RVEDV]、每搏输出量[RVSV]和射血分数[RVEF]）方面的一致性。
结果
对30名个体（19名男性；48±14岁）的分析显示，比较标准参考值和屏气测量的右心室舒张末期容积（153.7 vs 153.6 mL，P = 0.96）、收缩末期容积（71.6 vs 72.1 mL，P = 0.78）、每搏输出量（82.0 vs 81.6 mL，P = 0.65）和射血分数（54.9% vs 54.2%，P = 0.19）时，无显著差异。比较标准参考值和非屏气测量的右心室舒张末期容积（153.7 vs 152.2 mL，P = 0.34）、收缩末期容积（71.6 vs 72.
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