Department of Cardiology, The First Hospital of China Medical University, 155 Nanjing North Street, Heping District, Shenyang 110001, China.
Eur J Intern Med. 2016 Apr;29:32-6. doi: 10.1016/j.ejim.2016.01.019. Epub 2016 Feb 16.
The first objective was to examine whether A Body Shape Index (ABSI) and Body Roundness Index (BRI) can identify hyperuricemia in rural China. The second aim was to compare the relative strength of association between anthropometric indices and hyperuricemia.
A total of 11,345 participants were involved in this cross-sectional study. Obesity measurements included BMI, WC, WHtR, ABSI and BRI. According to the statistical distribution of serum uric acid (SUA), we split our study population in sex-specific tertiles of SUA.
After adjusting for confounding variables, BRI (linear regression: 0.170; AUC: 0.641; OR: 1.459) showed more powerful predictive ability for hyperuricemia than BMI (linear regression: 0.151; AUC: 0.630; OR: 1.108), while having a similar predictive power for hyperuricemia as WHtR (linear regression: 0.191; AUC: 0.656; OR: 1.067) and WC (linear regression: 0.209; AUC: 0.658; OR: 1.047) in the female group, but not in the male group. However, ABSI (A) (linear regression: 0.089 for women, 0.121 for men; AUC: 0.589 for women, 0.578 for men; OR: 1.027 for women, 1.034 for men) and ABSI (B) (linear regression: 0.118 for women, 0.121 for men; AUC: 0.607 for women, 0.578 for men; OR: 1.049 for women, 1.034 for men) had the lowest predictive power for hyperuricemia in both sex categories.
ABSI, BRI, BMI, WC and WHtR were all significantly associated with hyperuricemia in both sexes. In addition, BRI rather than ABSI showed a superior predictive ability for identifying hyperuricemia than BMI in female and similar capabilities as those of WC and WHtR in the female, but not in the male gender.
第一项目的是检验体脂肪分布指数（ABSI）和身体圆润指数（BRI）是否可以在中国农村地区识别出高尿酸血症。第二项目的是比较人体测量指数与高尿酸血症之间关联的相对强度。
本横断面研究共纳入 11345 名参与者。肥胖测量指标包括 BMI、WC、WHtR、ABSI 和 BRI。根据血清尿酸（SUA）的统计分布，我们将研究人群按 SUA 的性别特异性三分位数进行分组。
在校正混杂变量后，BRI（线性回归：0.170；AUC：0.641；OR：1.459）在预测女性高尿酸血症方面的能力强于 BMI（线性回归：0.151；AUC：0.630；OR：1.108），而与 WHtR（线性回归：0.191；AUC：0.656；OR：1.067）和 WC（线性回归：0.209；AUC：0.658；OR：1.047）在预测女性高尿酸血症方面的能力相似，但在男性中并非如此。然而，ABSI（A）（女性线性回归：0.089，男性线性回归：0.121；AUC：女性 0.589，男性 0.578；OR：女性 1.027，男性 1.034）和 ABSI（B）（女性线性回归：0.118，男性线性回归：0.121；AUC：女性 0.607，男性 0.578；OR：女性 1.049，男性 1.034）在两性中对高尿酸血症的预测能力最低。
ABSI、BRI、BMI、WC 和 WHtR 在两性中均与高尿酸血症显著相关。此外，BRI 而不是 ABSI 在女性中比 BMI 具有更好的识别高尿酸血症的预测能力，在女性中与 WC 和 WHtR 的能力相似，但在男性中并非如此。
