Chung Jonathan H, Lynch David A
1 Department of Radiology, The University of Chicago Medicine, 5841 S Maryland Ave, P210B, Chicago, IL 60637.
2 Department of Radiology, National Jewish Health, Denver, CO.
AJR Am J Roentgenol. 2016 Mar;206(3):463-71. doi: 10.2214/AJR.15.15627.
Multidisciplinary discussion is essential in establishing the diagnosis of idiopathic pulmonary fibrosis (IPF) and in determining prognosis.
The CT and histopathologic correlate for IPF is usual interstitial pneumonitis (UIP). If a high-confidence diagnosis of UIP is made on CT, IPF is almost always the diagnosis, obviating lung biopsy. If a confident diagnosis of UIP cannot be made on CT, further assessment with lung biopsy and multidisciplinary discussion are often necessary to achieve a confident final diagnosis.
多学科讨论对于特发性肺纤维化(IPF)的诊断确立及预后判定至关重要。
IPF的CT表现与组织病理学对应关系为普通型间质性肺炎(UIP)。若CT上能做出高置信度的UIP诊断,几乎总能诊断为IPF,无需进行肺活检。若CT上无法做出UIP的确定性诊断,通常需要通过肺活检及多学科讨论进行进一步评估,以得出确定性的最终诊断。