Santoro Frank A, Huang John
Department of Dermatology, University of Connecticut Health Center, 21 South Road, 2nd Floor, Farmington, CT 06032.
Department of Ophthalmology and Visual Science, Yale University School of Medicine, 40 Temple Street, Suite 3D, New Haven, CT 06510.
Clin Dermatol. 2016 Mar-Apr;34(2):138-45. doi: 10.1016/j.clindermatol.2015.11.011. Epub 2015 Nov 22.
Connective tissue disorders commonly involve multiple organ systems including the skin and eye. The pathogenesis of many of these disorders affects the microvasculature in these organs. Redness, dryness, pain, and vision loss might be signs of ocular disease in a patient with connective tissue disease. Ocular involvement can potentially lead to blindness and indicate systemic involvement. Dermatologists should be aware of potential ocular involvement in cutaneous connective tissue disorders, and their recognition should prompt ophthalmologic evaluation.
结缔组织疾病通常累及包括皮肤和眼睛在内的多个器官系统。这些疾病中的许多疾病的发病机制会影响这些器官的微血管系统。发红、干燥、疼痛和视力丧失可能是结缔组织病患者眼部疾病的体征。眼部受累可能会导致失明,并提示全身受累。皮肤科医生应意识到皮肤结缔组织疾病可能累及眼部,一旦发现应促使患者进行眼科评估。