Pang Jing, Lansberg Peter J, Watts Gerald F
School of Medicine and Pharmacology, University of Western Australia.
J Atheroscler Thromb. 2016 May 2;23(5):505-19. doi: 10.5551/jat.34108. Epub 2016 Feb 23.
Several international guidelines and consensus statements have recently been published on the care of familial hypercholesterolemia (FH)(1-3)). They agree on approaches to case detection and cascade testing, protocols in children, lifestyle and drug treatment strategies, and indications for lipoprotein apheresis. However, most countries in the world still do not have integrated, systematic FH screening programs to adequately detect and treat cases in the community. This study provides a comprehensive overview of recent and future international initiatives for closing the gaps in the care of FH.
最近已经发布了几份关于家族性高胆固醇血症(FH)护理的国际指南和共识声明(1-3)。它们在病例检测和级联检测方法、儿童治疗方案、生活方式和药物治疗策略以及脂蛋白分离术的适应症等方面达成了一致。然而,世界上大多数国家仍然没有综合、系统的FH筛查项目,无法在社区中充分检测和治疗病例。本研究全面概述了近期和未来旨在弥合FH护理差距的国际倡议。