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全结肠切除术后的增殖性脓皮病

Pyodermatitis vegetans after total colectomy.

作者信息

Uzunçakmak Tuğba Kevser, Akdeniz Necmettin, Karadağ Ayşe Serap, Çobanoğlu Bengü

机构信息

Department of Dermatology, Goztepe Research and Training Hospital, Istanbul Medeniyet University, Istanbul, Turkey.

Department of Pathology, Goztepe Research and Training Hospital, Istanbul Medeniyet University, Istanbul, Turkey.

出版信息

Indian Dermatol Online J. 2015 Dec;6(Suppl 1):S9-S11. doi: 10.4103/2229-5178.171052.

Abstract

Pyostomatitis-pyodermatitis vegetans (PPV) is a rare dermatological manifestation of inflammatory bowel disease, characterized by erythematous, vesiculopustular, exudative, annular, and/or vegetating plaques over the intertriginous regions that may precede or appear at the same time as the mucosal lesions. Systemic corticosteroids, dapsone, sulfasalazine, azathioprine, cyclosporine, and subtotal/total colectomy are the most common treatment options. A 16-year-old male patient presented to our outpatient clinic with a four months history of thickly crusted erosions on his trunk, back, and lower extremity. He had ulcerative colitis for four years and total colectomy was done seven months ago. Clinical and histopathological examination of his lesions were consistent with pyostomatitis vegetans. Although subtotal/total colectomy has been reported as a treatment option for PPV, lesions reappeared three months after total colectomy in our patient.

摘要

脓性口炎-脓性增殖性皮炎(PPV)是炎症性肠病罕见的皮肤表现,其特征为在摩擦部位出现红斑、水疱脓疱、渗出性、环状和/或增殖性斑块,这些斑块可能先于黏膜病变出现或与黏膜病变同时出现。全身用皮质类固醇、氨苯砜、柳氮磺胺吡啶、硫唑嘌呤、环孢素以及次全/全结肠切除术是最常见的治疗选择。一名16岁男性患者到我们门诊就诊,其躯干、背部和下肢有4个月厚痂性糜烂病史。他患溃疡性结肠炎4年,7个月前接受了全结肠切除术。对其病变进行的临床和组织病理学检查与脓性口炎一致。虽然次全/全结肠切除术已被报道为PPV的一种治疗选择,但在我们的患者中,全结肠切除术后3个月病变复发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a622/4738526/2e5aa2fc482f/IDOJ-6-9-g001.jpg

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