Keitley James, Griffin Liezel, Motta Luisa, Ferguson Janice, Young Helen
Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.
Department of Dermatology, Salford Royal NHS Foundation Trust, Salford, UK.
BMJ Case Rep. 2017 Oct 13;2017:bcr-2017-220779. doi: 10.1136/bcr-2017-220779.
We describe a case of disfiguring facial pyoderma vegetans in order to highlight the challenges in managing this rare skin condition and review the literature.A 54-year-old woman presented to dermatology clinic with a 3-month history of a left-sided facial lesion, which had been treated as an infected sebaceous cyst. The lesion had dramatically increased in size in the weeks prior to presentation. There was a history of Crohn's disease and ileal adenocarcinoma, both of which were in remission. A clinical diagnosis of pyoderma vegetans was made and the patient responded well to immunosuppressive therapy with oral ciclosporin. Carbon dioxide (CO) laser resurfacing to residual scarring contributed to an excellent cosmetic result.
我们描述了一例毁容性面部增殖性脓皮病病例,以突出管理这种罕见皮肤病的挑战并回顾相关文献。一名54岁女性因左侧面部病变3个月就诊于皮肤科诊所,该病变此前被当作感染性皮脂腺囊肿治疗。在就诊前几周,病变大小急剧增加。患者有克罗恩病和回肠腺癌病史,两者均处于缓解期。做出了增殖性脓皮病的临床诊断,患者对口服环孢素免疫抑制治疗反应良好。针对残留瘢痕的二氧化碳(CO)激光换肤术取得了极佳的美容效果。