Athwal Ruvinder, Bhogal Ricky Harminder, Hodson James, Ramcharan Sean
1 Warwick Hospital, Lakin Road, Warwick CV34 5BW, UK ; 2 University of Birmingham, Edgbaston, Birmingham, West Midlands B15 2TT, UK.
Hepatobiliary Surg Nutr. 2016 Feb;5(1):53-7. doi: 10.3978/j.issn.2304-3881.2015.11.02.
Pregnancy was traditionally considered a contraindication to cholecystectomy but is now becoming the favoured option for gallstone-related disease (GRD) during pregnancy.
To assess if cholecystectomy during pregnancy increases the risk of preterm labour, fetal mortality and maternal mortality. PubMed and MEDLINE databases for the period from January 1966 through December 2013. Studies were both conservative and surgical intervention was utilised in the management of GRD were included. The results of the included studies were pooled using meta-analysis techniques.
Surgical intervention for GRD in pregnancy does not increase the risk of preterm labour, fetal mortality or maternal mortality.
Cholecystectomy during pregnancy for GRD is associated with low complications for the fetus and mother and should be considered in all suitable patients.
传统上认为怀孕是胆囊切除术的禁忌症,但现在它正成为孕期胆结石相关疾病(GRD)的首选治疗方案。
为评估孕期胆囊切除术是否会增加早产、胎儿死亡和产妇死亡的风险。检索1966年1月至2013年12月期间的PubMed和MEDLINE数据库。纳入了对GRD的治疗采用保守治疗和手术干预的研究。使用荟萃分析技术汇总纳入研究的结果。
孕期对GRD进行手术干预不会增加早产、胎儿死亡或产妇死亡的风险。
孕期因GRD行胆囊切除术对胎儿和母亲的并发症发生率较低,所有合适的患者都应考虑进行该手术。