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本文引用的文献

1
SAGES guidelines for the use of laparoscopy during pregnancy.SAGES关于孕期腹腔镜检查使用的指南。
Surg Endosc. 2017 Oct;31(10):3767-3782. doi: 10.1007/s00464-017-5637-3. Epub 2017 Jun 22.
2
Interventions for treating hyperemesis gravidarum: a Cochrane systematic review and meta-analysis.治疗妊娠剧吐的干预措施:一项Cochrane系统评价和荟萃分析
J Matern Fetal Neonatal Med. 2018 Sep;31(18):2492-2505. doi: 10.1080/14767058.2017.1342805. Epub 2017 Jul 11.
3
Changing management of gallstone-related disease in pregnancy - a retrospective cohort analysis.妊娠期胆结石相关疾病管理的变化——一项回顾性队列分析
Scand J Gastroenterol. 2017 Sep;52(9):1016-1021. doi: 10.1080/00365521.2017.1333627. Epub 2017 Jun 9.
4
Age-related differences pre-, intra-, and postcholecystectomy: A retrospective cohort study of 6,868 patients.年龄相关的术前、术中及术后胆囊切除差异:6868 例患者的回顾性队列研究。
Int J Surg. 2017 Mar;39:119-126. doi: 10.1016/j.ijsu.2017.01.046. Epub 2017 Jan 16.
5
Laparoscopic versus open cholecystectomy in pregnancy: a systematic review and meta-analysis.妊娠期腹腔镜与开腹胆囊切除术:一项系统评价与荟萃分析
Surg Endosc. 2017 Feb;31(2):673-679. doi: 10.1007/s00464-016-5019-2. Epub 2016 Jun 20.
6
Surgery for gallstone disease during pregnancy does not increase fetal or maternal mortality: a meta-analysis.孕期胆结石疾病手术不会增加胎儿或产妇死亡率:一项荟萃分析。
Hepatobiliary Surg Nutr. 2016 Feb;5(1):53-7. doi: 10.3978/j.issn.2304-3881.2015.11.02.
7
Implications of gallbladder cholesterolosis and cholesterol polyps?胆囊胆固醇沉着症和胆固醇息肉的影响?
J Surg Res. 2016 Feb;200(2):467-72. doi: 10.1016/j.jss.2015.08.037. Epub 2015 Aug 28.
8
Exposure to prescription opioid analgesics in utero and risk of neonatal abstinence syndrome: population based cohort study.子宫内暴露于处方阿片类镇痛药与新生儿戒断综合征风险:基于人群的队列研究
BMJ. 2015 May 14;350:h2102. doi: 10.1136/bmj.h2102.
9
Non-operative management of symptomatic cholelithiasis in pregnancy is associated with frequent hospitalizations.妊娠期有症状胆结石的非手术治疗与频繁住院相关。
J Gastrointest Surg. 2015 Apr;19(4):598-603. doi: 10.1007/s11605-015-2757-8. Epub 2015 Feb 4.
10
Laparoscopy in cholecysto-choledocholithiasis.腹腔镜胆囊-胆总管结石病。
Best Pract Res Clin Gastroenterol. 2014 Feb;28(1):195-209. doi: 10.1016/j.bpg.2013.11.015. Epub 2013 Dec 6.

妊娠期胆固醇沉着症所致腹痛与呕吐

Abdominal pain and vomiting during pregnancy due to cholesterolosis.

作者信息

van Limburg Stirum Emilie Vj, van Pampus Maria G, Jansen Jeroen M, Janszen Erica Wm

机构信息

Department of Obstetrics and Gynecology, OLVG, Amsterdam, The Netherlands.

Department of Gastro-enterology, OLVG, Amsterdam, The Netherlands.

出版信息

BMJ Case Rep. 2019 Mar 20;12(3):e227826. doi: 10.1136/bcr-2018-227826.

DOI:10.1136/bcr-2018-227826
PMID:30898960
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6453260/
Abstract

We present a 22-year-old pregnant woman at 15 weeks of gestation, with abdominal pain and vomiting. We demonstrate that diagnosis and treatment of vomiting and abdominal pain in pregnancy can be difficult. Therefore, involvement of other medical specialists is important when common treatments fail. Cholesterolosis can cause symptoms similar to those caused by cholelithiasis. Controversial to gallstones, identification of cholesterolosis by ultrasound is hard. Cholecystectomy is the only effective treatment option for cholesterolosis and can be performed safely during pregnancy. Cholecystectomy in pregnancy should be considered if, despite atypical symptoms, gallbladder disease is suspected and other diagnoses are ruled out. This may reduce recurrent symptoms, hospital admissions, exposure to harmful drugs and obstetric complications.

摘要

我们报告一名妊娠15周的22岁孕妇,伴有腹痛和呕吐。我们证明,妊娠呕吐和腹痛的诊断与治疗可能具有挑战性。因此,当常规治疗无效时,其他医学专家的参与很重要。胆固醇沉着症可引起与胆石症相似的症状。与胆结石不同的是,通过超声识别胆固醇沉着症很困难。胆囊切除术是胆固醇沉着症唯一有效的治疗选择,并且可以在孕期安全进行。如果尽管症状不典型,但怀疑有胆囊疾病且排除了其他诊断,则应考虑在孕期行胆囊切除术。这可能会减少复发症状、住院次数、有害药物暴露及产科并发症。