囊性纤维化患儿营养不良的生长评估及危险因素
Growth assessment and risk factors of malnutrition in children with cystic fibrosis.
作者信息
Isa Hasan M, Al-Ali Lina F, Mohamed Afaf M
机构信息
Pediatric Department, Salmaniya Medical Complex, Manama, Kingdom of Bahrain. E-mail.
出版信息
Saudi Med J. 2016 Mar;37(3):293-8. doi: 10.15537/smj.2016.3.13476.
OBJECTIVES
To evaluate the nutritional status, to screen for the presence of malnutrition, and to study the possible risk factors associated with malnutrition in patients with cystic fibrosis (CF).
METHODS
A retrospective cross-sectional review of medical records of all diagnosed CF patients in the Pediatric Department, Salmaniya Medical Complex, Manama, Kingdom of Bahrain, between January 1984 and May 2015 was conducted. Demographic and anthropometric data were collected from records of last visit to CF clinic. Nutritional status and risk factors of malnutrition were assessed.
RESULTS
All records of 109 CF patients were reviewed. Forty-seven pediatric patients were included in the study. All included patients were on pancreatic enzyme replacement and 42 (89%) received high-calorie supplementation. Growth failure was noted in 34 (72%) patients, 19 (56%) were wasted and stunted, 8 (23.5%) were wasted only, and 7 (20.5%) were stunted. Low birth weight (p=0.032), and the presence of gastroesophageal reflux disease (GERD) (p=0.039) were the significant risk factors for malnutrition.
CONCLUSIONS
Most CF patients in Bahrain (72%) are malnourished. Low birth weight and the presence of GERD are risk factors.
目的
评估囊性纤维化（CF）患者的营养状况，筛查营养不良情况，并研究与营养不良相关的可能风险因素。
方法
对1984年1月至2015年5月间巴林王国麦纳麦萨勒曼尼亚医疗中心儿科所有确诊CF患者的病历进行回顾性横断面研究。从CF诊所最后一次就诊记录中收集人口统计学和人体测量数据。评估营养状况和营养不良风险因素。
结果
对109例CF患者的所有记录进行了审查。47例儿科患者纳入研究。所有纳入患者均接受胰酶替代治疗，42例（89%）接受高热量补充。34例（72%）患者出现生长发育迟缓，19例（56%）消瘦且发育迟缓，8例（23.5%）仅消瘦，7例（20.5%）仅发育迟缓。低出生体重（p = 0.032）和胃食管反流病（GERD）的存在（p = 0.039）是营养不良的重要风险因素。
结论
巴林大多数CF患者（72%）营养不良。低出生体重和GERD的存在是风险因素。
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