Krzymowski T, Stefańczyk-Krzymowska S, Koziorowski M
Department of Animal Physiology, School of Agriculture and Technology, Olsztyn.
Acta Physiol Pol. 1989 Jan-Feb;40(1):23-34.
A new concept has been presented on the mechanism protecting the corpus luteum during oestrous cycle, early pregnancy and pseudopregnancy induced by oestrogens. The concept is based on the recently discovered mechanism of back transfer of prostaglandin F2 alpha from the broad ligament vasculature into the uterus and on the participation of oestrogen in this process. The morphological facilitates for counter-current transfer of PGF2 alpha in the area of mesometrial vasculature and ability the uterus to bind PGF2 alpha were presented. It has been concluded that the process of PGF2 alpha back-transfer from mesometrial vasculature into the uterus may reduce in uterine venous blood the amplitude of PGF2 alpha pulses and by this way may reduce the penetration of prostaglandin into subovarian area and from there to the corpus luteum.
关于雌激素诱导的发情周期、早期妊娠和假孕期间保护黄体的机制，已提出了一个新的概念。这一概念基于最近发现的前列腺素F2α从阔韧带脉管系统逆向转移至子宫的机制，以及雌激素在这一过程中的参与。文中介绍了在子宫系膜脉管区域前列腺素F2α逆流转移的形态学促进因素以及子宫结合前列腺素F2α的能力。得出的结论是，前列腺素F2α从子宫系膜脉管系统逆向转移至子宫的过程可能会降低子宫静脉血中前列腺素F2α脉冲的幅度，从而减少前列腺素向卵巢下区域的渗透以及从该区域到黄体的渗透。
