Burakgazi Ahmet Z, AlMahameed Soufian
*Department of Medicine, MDA/ALS Clinic at Carilion Clinic, Roanoke, VA; Virginia Tech Carilion School of Medicine and Research Institute; and †Department of Medicine, Carilion Clinic Heart Rhythm Services; Virginia Tech Carilion School of Medicine and Research Institute.
J Clin Neuromuscul Dis. 2016 Mar;17(3):120-8. doi: 10.1097/CND.0000000000000106.
Cardiac autonomic neuropathy (CAN) is the least recognized and understood complication of peripheral neuropathy. However, because of its potential adverse effects including sudden death, CAN is one of the most important forms of autonomic neuropathies. CAN presents with different clinical manifestations including postural hypotension, exercise intolerance, fluctuation of blood pressure and heart rate, arrhythmia, and increased risk of myocardial infarction. In this article, the prevalence, clinical presentations, and management of cardiac involvement in certain peripheral neuropathies, including diabetic neuropathy, Guillain-Barré syndrome, chronic inflammatory polyneuropathy, human immunodeficiency virus-associated neuropathy, hereditary neuropathies, and amyloid neuropathy are examined in detail.
心脏自主神经病变（CAN）是周围神经病变中最不为人所认识和理解的并发症。然而，由于其包括猝死在内的潜在不良影响，CAN是自主神经病变最重要的形式之一。CAN表现出不同的临床表现，包括体位性低血压、运动不耐受、血压和心率波动、心律失常以及心肌梗死风险增加。在本文中，将详细探讨某些周围神经病变（包括糖尿病性神经病变、吉兰-巴雷综合征、慢性炎性多发性神经病变、人类免疫缺陷病毒相关性神经病变、遗传性神经病变和淀粉样神经病变）中心脏受累的患病率、临床表现及管理。
