Leng Bing, Han Siyuan, Bao Yijun, Zhang Hongliang, Wang Yong, Wu Yupeng, Wang Yibao
Department of Neurosurgery, the First Affiliated Hospital of China Medical University, No.155, North Nanjing Street, Heping District, Shenyang, 110001, Liaoning, People's Republic of China.
Department of Plastic Surgery, the First Affiliated Hospital of China Medical University, Shenyang, Liaoning, People's Republic of China.
Neuroradiology. 2016 Jun;58(6):595-606. doi: 10.1007/s00234-016-1650-9. Epub 2016 Feb 23.
The definitive structure and comprehensive role of the uncinate fasciculus (UF) are still obscure. We aimed to map the human UF white matter tractography and investigate the asymmetry, connectivity, and segmentation of the UF.
Subcomponents of the UF were analyzed in 9 normal subjects and a 30-subject diffusion spectrum imaging (DSI) template (CMU-30). DSI and microdissection were performed to explore the tractography of the UF.
Both methods revealed that it connects the anterior part of the temporal lobe (superior temporal gyrus and temporal pole) with the inferior frontal cortex and the orbitofrontal cortex. The UF starts at the temporal gyrus, runs inferiorly to the inferior frontal occipital fasciculus and splits into two branches, terminating in the ventrolateral frontal cortex and the rostral middle frontal cortex. Our study showed that the cortical areas of termination in the frontal lobe of the UF are the pars triangularis and pars orbitalis. The relative volume of the UF in both hemispheres was calculated. An independent t test was used to determine variances in the value of tract volume between the left and right hemispheres. The volume and the length showed a significant statistical difference in the total volume of the UF. We suggest the UF is leftward asymmetry.
The two parts of the UF were divided, but the conclusion is not consistent with the previous published articles which have shown that the UF is segmented into three parts. Our research facilitates a better understanding of the UF.
钩束（UF）的确切结构和全面作用仍不明确。我们旨在绘制人类钩束的白质纤维束成像图，并研究钩束的不对称性、连接性和分段情况。
在9名正常受试者和一个包含30名受试者的扩散光谱成像（DSI）模板（CMU - 30）中分析钩束的子成分。进行DSI和显微解剖以探索钩束的纤维束成像。
两种方法均显示，钩束将颞叶前部（颞上回和颞极）与额下回和眶额皮质相连。钩束起始于颞回，向下走行至额枕下束，并分成两个分支，终止于腹外侧额叶皮质和额中回前部。我们的研究表明，钩束在额叶的终止皮质区域为三角部和眶部。计算了两侧半球钩束的相对体积。使用独立t检验来确定左右半球之间纤维束体积值的差异。钩束的总体积在体积和长度上显示出显著的统计学差异。我们认为钩束存在左侧不对称性。
钩束分为两部分，但这一结论与之前发表的表明钩束分为三部分的文章不一致。我们的研究有助于更好地理解钩束。
