Schmidt-Malan Suzannah M, Greenwood Quaintance Kerryl E, Karau Melissa J, Patel Robin
Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA.
Division of Infectious Diseases, Department of Medicine, Mayo Clinic, Rochester, MN 55905, USA; Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA.
Diagn Microbiol Infect Dis. 2016 May;85(1):77-9. doi: 10.1016/j.diagmicrobio.2016.01.008. Epub 2016 Jan 12.
We determined the MIC and minimum biofilm bactericidal concentration (MBBC) of tedizolid and vancomycin against 97 isolates of Staphylococcus aureus and 74 isolates of Staphylococcus epidermidis associated with prosthetic joint infection. All isolates were vancomycin susceptible in the planktonic state; all staphylococci studied had a tedizolid MIC ≤0.5 μg/mL. The MBBC90 was >32 and >128 μg/mL for tedizolid and vancomycin, respectively.
我们测定了替加环素和万古霉素对97株与人工关节感染相关的金黄色葡萄球菌及74株表皮葡萄球菌的最低抑菌浓度（MIC）和最低生物被膜杀菌浓度（MBBC）。所有分离株在浮游状态下对万古霉素敏感；所有研究的葡萄球菌的替加环素MIC均≤0.5μg/mL。替加环素和万古霉素的MBBC90分别>32μg/mL和>128μg/mL。
