用于新生儿无创呼吸支持的高频通气
High-frequency ventilation for non-invasive respiratory support of neonates.
作者信息
Yoder Bradley A, Albertine K H, Null D M
机构信息
Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT, USA.
Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT, USA.
出版信息
Semin Fetal Neonatal Med. 2016 Jun;21(3):162-73. doi: 10.1016/j.siny.2016.02.001. Epub 2016 Feb 18.
Abstract
Non-invasive respiratory support is increasingly used in lieu of intubated ventilator support for the management of neonatal respiratory failure, particularly in very low birth weight infants at risk for bronchopulmonary dysplasia. The optimal approach and mode for non-invasive support remains uncertain. This article reviews the application of high-frequency ventilation for non-invasive respiratory support in neonates, including basic science studies on mechanics of gas exchange, animal model investigations, and a review of current clinical use in human neonates.
摘要
在新生儿呼吸衰竭的管理中，无创呼吸支持越来越多地被用于替代气管插管通气支持，尤其是在有支气管肺发育不良风险的极低出生体重儿中。无创支持的最佳方法和模式仍不确定。本文综述了高频通气在新生儿无创呼吸支持中的应用，包括气体交换力学的基础科学研究、动物模型研究以及对人类新生儿当前临床应用的综述。
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