Finn Elizabeth H, Misteli Tom, Shachar Sigal
National Cancer Institute, NIH, Bethesda, MD 20892, USA.
National Cancer Institute, NIH, Bethesda, MD 20892, USA.
Dev Cell. 2016 Feb 22;36(4):356-7. doi: 10.1016/j.devcel.2016.02.002.
Elucidating chromatin's 3D shape is critical to understanding its function, but the fine structure of chromatin domains remains poorly resolved. In a recent report in Nature, Boettiger et al. (2016) visualize chromatin in super-resolution, gaining unprecedented insight into chromatin architecture.
阐明染色质的三维形状对于理解其功能至关重要,但染色质结构域的精细结构仍未得到很好的解析。在最近发表于《自然》杂志的一篇报告中,博伊蒂格等人(2016年)以超分辨率观察染色质,对染色质结构有了前所未有的深入了解。