Villanueva-Perez Pablo, Pedrini Bill, Mokso Rajmund, Guizar-Sicairos Manuel, Arcadu Filippo, Stampanoni Marco
Opt Express. 2016 Feb 22;24(4):3189-201. doi: 10.1364/OE.24.003189.
We propose a signal-to-noise criterion which predicts whether a feature of a given size and scattering strength, placed inside a larger object, can be retrieved with two common X-ray imaging techniques: coherent diffraction imaging and projection microscopy. This criterion, based on how efficiently these techniques detect the scattered photons and validated through simulations, shows in general that projection microscopy can resolve smaller phase differences and features than coherent diffraction imaging. Our criterion can be used to design optimized imaging experiments and perform feasibility studies for sensitive biological materials in free-electron lasers, where the number of photons per pulse is limited, or in synchrotron experiments, for both techniques.
我们提出了一种信噪比标准，该标准可预测放置在较大物体内部的给定尺寸和散射强度的特征能否通过两种常见的X射线成像技术来获取：相干衍射成像和投影显微镜。基于这些技术检测散射光子的效率并通过模拟验证的该标准总体表明，投影显微镜比相干衍射成像能够分辨更小的相位差和特征。我们的标准可用于设计优化的成像实验，并对自由电子激光器（其中每个脉冲的光子数量有限）中的敏感生物材料或同步加速器实验中的这两种技术进行可行性研究。
