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术前最大呼气压力与心脏手术后有创机械通气时间相关:一项观察性研究。

Preoperative maximal expiratory pressure is associated with duration of invasive mechanical ventilation after cardiac surgery: An observational study.

作者信息

Zanini Maurice, Nery Rosane Maria, Buhler Raquel Petry, de Lima Juliana Beust, Stein Ricardo

机构信息

Federal University of Rio Grande do Sul, Hospital de Clínicas de Porto Alegre, Brazil.

Physical Medicine and Rehabilitation Division, Hospital de Clínicas de Porto Alegre, Brazil.

出版信息

Heart Lung. 2016 May-Jun;45(3):244-8. doi: 10.1016/j.hrtlng.2016.01.003. Epub 2016 Feb 20.

DOI:10.1016/j.hrtlng.2016.01.003
PMID:26907196
Abstract

OBJECTIVE

To evaluate the association of maximal expiratory pressure (MEP), maximal inspiratory pressure (MIP), and peak expiratory flow (PEF) with total duration of invasive mechanical ventilation (IMV) in subjects undergoing cardiac surgery.

BACKGROUND

Prolonged IMV is associated with respiratory infections, prolonged hospitalization, and increased mortality. Pulmonary function tests can help predict postoperative outcomes after cardiac surgery.

METHODS

We recruited subjects admitted for cardiac surgery. All MIP, MEP, and PEF measurements were performed before surgery. Multivariable analysis was performed using a multiple linear regression model to control for possible confounders and test for association of MIP, MEP, and PEF with IMV duration.

RESULTS

Overall, 125 subjects were included in the study. Higher MEP was associated with reduced duration of IMV after adjustment for confounders (P = 0.015), but no such association was observed between MIP or PEF and IMV.

CONCLUSIONS

In subjects undergoing elective cardiac surgery, preoperative MEP is associated with IMV duration.

摘要

目的

评估心脏手术患者的最大呼气压力(MEP)、最大吸气压力(MIP)和呼气峰值流速(PEF)与有创机械通气(IMV)总时长之间的关联。

背景

长时间的IMV与呼吸道感染、住院时间延长及死亡率增加相关。肺功能测试有助于预测心脏手术后的术后结局。

方法

我们招募了因心脏手术入院的患者。所有MIP、MEP和PEF测量均在手术前进行。使用多元线性回归模型进行多变量分析,以控制可能的混杂因素,并检验MIP、MEP和PEF与IMV时长之间的关联。

结果

总体而言,125名患者纳入了研究。在对混杂因素进行校正后,较高的MEP与IMV时长缩短相关(P = 0.015),但未观察到MIP或PEF与IMV之间存在此类关联。

结论

在接受择期心脏手术的患者中,术前MEP与IMV时长相关。

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