• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

清酒蛋白补充剂对力量训练小鼠的运动表现和生化指标有影响。

Sake Protein Supplementation Affects Exercise Performance and Biochemical Profiles in Power-Exercise-Trained Mice.

作者信息

Chen Yi-Ming, Lin Che-Li, Wei Li, Hsu Yi-Ju, Chen Kuan-Neng, Huang Chi-Chang, Kao Chin-Hsung

机构信息

Graduate Institute of Sports Science, National Taiwan Sport University, Taoyuan 33301, Taiwan.

Department of Orthopedic Surgery, Taipei Medical University-Shuang Ho Hospital, New Taipei City 23561, Taiwan.

出版信息

Nutrients. 2016 Feb 20;8(2):106. doi: 10.3390/nu8020106.

DOI:10.3390/nu8020106
PMID:26907336
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4772068/
Abstract

UNLABELLED

Exercise and fitness training programs have attracted the public's attention in recent years. Sports nutrition supplementation is an important issue in the global sports market.

PURPOSE

In this study, we designed a power exercise training (PET) program with a mouse model based on a strength and conditional training protocol for humans. We tested the effect of supplementation with functional branched-chain amino acid (BCAA)-rich sake protein (SP) to determine whether the supplement had a synergistic effect during PET and enhanced athletic performance and resistance to fatigue.

METHODS

Male ICR mice were divided into three groups (n = 8 per group) for four-week treatment: sedentary controls with vehicle (SC), and PET and PET groups with SP supplementation (3.8 g/kg, PET + SP). Exercise performance was evaluated by forelimb grip strength and exhaustive swimming time as well as changes in body composition and anti-fatigue activity levels of serum lactate, ammonia, glucose, and creatine kinase (CK) after a 15-min swimming exercise. The biochemical parameters were measured at the end of the experiment.

RESULTS

four-week PET significantly increased grip strength and exhaustive swimming time and decreased epididymal fat pad (EFP) weight and area. Levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), creatinine, and uric acid (UA) were significantly increased. PET + SP supplementation significantly decreased serum lactate, ammonia and CK levels after the 15-min swimming exercise. The resting serum levels of AST, ALT, CREA and UA were all significantly decreased with PET + SP.

CONCLUSION

The PET program could increase the exercise performance and modulate the body composition of mice. PET with SP conferred better anti-fatigue activity, improved biochemical profiles, and may be an effective ergogenic aid in strength training.

摘要

未标注

近年来，运动和健身训练计划吸引了公众的关注。运动营养补充是全球体育市场中的一个重要问题。

目的

在本研究中，我们基于人类的力量和条件训练方案，用小鼠模型设计了一种动力运动训练（PET）计划。我们测试了补充富含功能性支链氨基酸（BCAA）的清酒蛋白（SP）的效果，以确定该补充剂在PET期间是否具有协同作用，并增强运动表现和抗疲劳能力。

方法

将雄性ICR小鼠分为三组（每组n = 8）进行为期四周的治疗：给予载体的久坐对照组（SC），以及补充SP（3.8 g/kg，PET + SP）的PET组和PET组。通过前肢握力、力竭游泳时间以及15分钟游泳运动后身体成分的变化和血清乳酸、氨、葡萄糖和肌酸激酶（CK）的抗疲劳活性水平来评估运动表现。在实验结束时测量生化参数。

结果

为期四周的PET显著增加了握力和力竭游泳时间，并降低了附睾脂肪垫（EFP）的重量和面积。天冬氨酸转氨酶（AST）、丙氨酸转氨酶（ALT）、肌酐和尿酸（UA）水平显著升高。补充PET + SP在15分钟游泳运动后显著降低了血清乳酸、氨和CK水平。PET + SP使AST、ALT、CREA和UA的静息血清水平均显著降低。

结论

PET计划可以提高小鼠的运动表现并调节其身体成分。PET与SP一起具有更好的抗疲劳活性，改善了生化指标，并且可能是力量训练中一种有效的促力辅助剂。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae81/4772068/97e4e542ed6b/nutrients-08-00106-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae81/4772068/d7bf579c7de5/nutrients-08-00106-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae81/4772068/6127a630e7b9/nutrients-08-00106-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae81/4772068/8055e8614f5a/nutrients-08-00106-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae81/4772068/038326a245b8/nutrients-08-00106-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae81/4772068/d3f3d9c4d2d4/nutrients-08-00106-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae81/4772068/a6660d198434/nutrients-08-00106-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae81/4772068/0ebb0471cf71/nutrients-08-00106-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae81/4772068/97e4e542ed6b/nutrients-08-00106-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae81/4772068/d7bf579c7de5/nutrients-08-00106-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae81/4772068/6127a630e7b9/nutrients-08-00106-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae81/4772068/8055e8614f5a/nutrients-08-00106-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae81/4772068/038326a245b8/nutrients-08-00106-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae81/4772068/d3f3d9c4d2d4/nutrients-08-00106-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae81/4772068/a6660d198434/nutrients-08-00106-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae81/4772068/0ebb0471cf71/nutrients-08-00106-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae81/4772068/97e4e542ed6b/nutrients-08-00106-g008.jpg

相似文献

1
Sake Protein Supplementation Affects Exercise Performance and Biochemical Profiles in Power-Exercise-Trained Mice.清酒蛋白补充剂对力量训练小鼠的运动表现和生化指标有影响。
Nutrients. 2016 Feb 20;8(2):106. doi: 10.3390/nu8020106.
2
Dehydroepiandrosterone Supplementation Combined with Whole-Body Vibration Training Affects Testosterone Level and Body Composition in Mice.脱氢表雄酮补充剂联合全身振动训练对小鼠睾酮水平和身体成分的影响
Int J Med Sci. 2016 Sep 16;13(10):730-740. doi: 10.7150/ijms.16132. eCollection 2016.
3
Effect of curcumin supplementation on physiological fatigue and physical performance in mice.姜黄素补充剂对小鼠生理疲劳和身体机能的影响。
Nutrients. 2015 Jan 30;7(2):905-21. doi: 10.3390/nu7020905.
4
Dehydroepiandrosterone supplementation combined with Weight-Loading Whole-Body Vibration Training (WWBV) affects exercise performance and muscle glycogen storage in middle-aged C57BL/6 mice.脱氢表雄酮补充联合负重全身振动训练（WWBV）影响中年 C57BL/6 小鼠的运动表现和肌肉糖原储存。
Int J Med Sci. 2018 Mar 9;15(6):564-573. doi: 10.7150/ijms.23352. eCollection 2018.
5
Ergogenic Effects of Green Tea Combined with Isolated Soy Protein on Increasing Muscle Mass and Exercise Performance in Resistance-Trained Mice.绿茶与分离大豆蛋白联合对增肌和抗阻训练小鼠运动表现的增效作用。
Nutrients. 2021 Dec 18;13(12):4547. doi: 10.3390/nu13124547.
6
Whey protein improves exercise performance and biochemical profiles in trained mice.乳清蛋白可改善训练小鼠的运动表现和生化指标。
Med Sci Sports Exerc. 2014 Aug;46(8):1517-24. doi: 10.1249/MSS.0000000000000272.
7
Effect of whole-body vibration training on body composition, exercise performance and biochemical responses in middle-aged mice.全身振动训练对中年小鼠身体成分、运动能力及生化反应的影响
Metabolism. 2015 Sep;64(9):1146-56. doi: 10.1016/j.metabol.2015.05.007. Epub 2015 May 15.
8
Capsaicin Supplementation Reduces Physical Fatigue and Improves Exercise Performance in Mice.补充辣椒素可减轻小鼠的身体疲劳并提高运动表现。
Nutrients. 2016 Oct 20;8(10):648. doi: 10.3390/nu8100648.
9
Isolated Soy Protein Supplementation and Exercise Improve Fatigue-Related Biomarker Levels and Bone Strength in Ovariectomized Mice.补充分离大豆蛋白和运动可改善去卵巢小鼠与疲劳相关的生物标志物水平和骨强度。
Nutrients. 2018 Nov 17;10(11):1792. doi: 10.3390/nu10111792.
10
Angelica sinensis improves exercise performance and protects against physical fatigue in trained mice.当归可提高训练小鼠的运动能力并预防身体疲劳。
Molecules. 2014 Mar 31;19(4):3926-39. doi: 10.3390/molecules19043926.

引用本文的文献

1
Specific muscle targeted delivery of miR-130a loaded lipid nanoparticles: a novel approach to inhibit lipid accumulation in skeletal muscle and obesity.靶向特定肌肉递送负载miR-130a的脂质纳米颗粒：一种抑制骨骼肌脂质积累和肥胖的新方法。
J Nanobiotechnology. 2025 Mar 3;23(1):159. doi: 10.1186/s12951-025-03225-0.
2
Fermented mixed grain ameliorates chronic stress-induced depression-like behavior and memory deficit.发酵混合谷物可改善慢性应激诱导的抑郁样行为和记忆缺陷。
Food Sci Biotechnol. 2023 Jul 27;33(4):969-979. doi: 10.1007/s10068-023-01387-x. eCollection 2024 Mar.
3
Polysaccharides from apple pomace exhibit anti-fatigue activity through increasing glycogen content.

本文引用的文献

1
The effects of cross-training on fitness and injury in women.交叉训练对女性体能和受伤情况的影响。
US Army Med Dep J. 2015 Apr-Jun:33-41.
2
Effect of curcumin supplementation on physiological fatigue and physical performance in mice.姜黄素补充剂对小鼠生理疲劳和身体机能的影响。
Nutrients. 2015 Jan 30;7(2):905-21. doi: 10.3390/nu7020905.
3
Fucoidan supplementation improves exercise performance and exhibits anti-fatigue action in mice.补充岩藻依聚糖可改善小鼠的运动表现并展现出抗疲劳作用。
苹果渣中的多糖通过增加糖原含量表现出抗疲劳活性。
J Food Sci Technol. 2023 Jan;60(1):283-291. doi: 10.1007/s13197-022-05613-y. Epub 2022 Nov 19.
4
Anti-Fatigue Effect of a Dietary Supplement from the Fermented By-Products of Taiwan Tilapia Aquatic Waste and Oligosaccharide Complex.一种源自台湾罗非鱼水产废弃物发酵副产物和寡糖复合物的膳食补充剂的抗疲劳作用。
Nutrients. 2021 May 15;13(5):1688. doi: 10.3390/nu13051688.
5
The effects of different types of aquatic exercise training interventions on a high-fructose diet-fed mice.不同类型的水上运动训练干预对高果糖饮食喂养小鼠的影响。
Int J Med Sci. 2021 Jan 1;18(3):695-705. doi: 10.7150/ijms.52347. eCollection 2021.
6
Nutritional and Functional Properties of Fermented Mixed Grains by Solid-State Fermentation with 245.利用245进行固态发酵的混合谷物发酵产物的营养与功能特性
Foods. 2020 Nov 19;9(11):1693. doi: 10.3390/foods9111693.
7
Supplementation of L-Arginine, L-Glutamine, Vitamin C, Vitamin E, Folic Acid, and Green Tea Extract Enhances Serum Nitric Oxide Content and Antifatigue Activity in Mice.补充L-精氨酸、L-谷氨酰胺、维生素C、维生素E、叶酸和绿茶提取物可提高小鼠血清一氧化氮含量并增强其抗疲劳活性。
Evid Based Complement Alternat Med. 2020 Apr 11;2020:8312647. doi: 10.1155/2020/8312647. eCollection 2020.
8
Novel individualized power training protocol preserves physical function in adult and older mice.新型个性化力量训练方案可维持成年和老年小鼠的身体机能。
Geroscience. 2019 Apr;41(2):165-183. doi: 10.1007/s11357-019-00069-z. Epub 2019 May 10.
9
Keto-Adaptation and Endurance Exercise Capacity, Fatigue Recovery, and Exercise-Induced Muscle and Organ Damage Prevention: A Narrative Review.酮适应与耐力运动能力、疲劳恢复及运动诱导的肌肉和器官损伤预防：一篇叙述性综述
Sports (Basel). 2019 Feb 13;7(2):40. doi: 10.3390/sports7020040.
10
Small Molecule Oligopeptides Isolated from Walnut ( L.) and Their Anti-Fatigue Effects in Mice.核桃（L.）中分离得到的小分子寡肽及其对小鼠抗疲劳作用的研究。
Molecules. 2018 Dec 22;24(1):45. doi: 10.3390/molecules24010045.
Nutrients. 2014 Dec 31;7(1):239-52. doi: 10.3390/nu7010239.
4
Whole-body vibration training effect on physical performance and obesity in mice.全身振动训练对小鼠身体机能和肥胖的影响。
Int J Med Sci. 2014 Sep 18;11(12):1218-27. doi: 10.7150/ijms.9975. eCollection 2014.
5
Effect of intestinal microbiota on exercise performance in mice.肠道微生物群对小鼠运动能力的影响。
J Strength Cond Res. 2015 Feb;29(2):552-8. doi: 10.1519/JSC.0000000000000644.
6
Chicken essence improves exercise performance and ameliorates physical fatigue.鸡精能提高运动表现，改善身体疲劳。
Nutrients. 2014 Jul 18;6(7):2681-96. doi: 10.3390/nu6072681.
7
Astragalus membranaceus improves exercise performance and ameliorates exercise-induced fatigue in trained mice.黄芪可提高训练小鼠的运动能力并减轻运动诱导的疲劳。
Molecules. 2014 Mar 3;19(3):2793-807. doi: 10.3390/molecules19032793.
8
Whey protein improves exercise performance and biochemical profiles in trained mice.乳清蛋白可改善训练小鼠的运动表现和生化指标。
Med Sci Sports Exerc. 2014 Aug;46(8):1517-24. doi: 10.1249/MSS.0000000000000272.
9
Myofibrillar muscle protein synthesis rates subsequent to a meal in response to increasing doses of whey protein at rest and after resistance exercise.在休息时和抗阻运动后，摄入不同剂量乳清蛋白后，餐后肌原纤维肌蛋白合成速率的变化。
Am J Clin Nutr. 2014 Jan;99(1):86-95. doi: 10.3945/ajcn.112.055517. Epub 2013 Nov 20.
10
Extreme conditioning programs and injury risk in a US Army Brigade Combat Team.美国陆军旅战斗队中的极限训练计划与受伤风险
US Army Med Dep J. 2013 Oct-Dec:36-47.