Mok Stephanie, Moraes Christopher
Department of Chemical Engineering, McGill University, Canada.
Integr Biol (Camb). 2016 Mar 14;8(3):262-6. doi: 10.1039/c6ib90008a.
The field of mechanobiology provides an integrative understanding of biology and engineering principles. Mechanical forces are now well-established to provide a physical stimulus to help maintain normal tissue function, yet little is understood as to how forces experienced at various length scales influence cell behaviour and tissue function. In this Research Highlight, we describe recent technical innovations that have enabled advanced insight into the cellular microenvironment across a range of length scales.
力学生物学领域提供了对生物学和工程学原理的综合理解。机械力现已被充分证实能提供一种物理刺激，以帮助维持正常的组织功能，但对于在各种长度尺度上所经历的力如何影响细胞行为和组织功能，我们却知之甚少。在本研究亮点中，我们描述了最近的技术创新，这些创新使我们能够在一系列长度尺度上深入了解细胞微环境。
