Bakir R, Lecapitaine A-L, Chevalier J, Juberthie B, Bouldouyre M-A, Gros H
Service de médecine interne et de maladies infectieuses, centre hospitalier Robert-Ballanger, 1, boulevard Robert-Ballanger, 93602 Aulnay-sous-Bois cedex, France.
Service de médecine interne et de maladies infectieuses, centre hospitalier Robert-Ballanger, 1, boulevard Robert-Ballanger, 93602 Aulnay-sous-Bois cedex, France.
Rev Med Interne. 2016 Nov;37(11):771-774. doi: 10.1016/j.revmed.2016.01.013. Epub 2016 Feb 19.
The histiocytic necrotizing lymphadenitis or Kikuchi-Fujimoto's disease is characterized by a lymph node inflammation whose similarity with systemic lupus is generally admitted.
Our description of two familial cases aims at raising the hypothesis of the existence of a genetic background in this disease following the example of what is observed in the autoimmune diseases.
Pathophysiology of Kikuchi-Fujimoto's disease is probably multifactorial and may include predisposing genetic background and a possible infectious triggering event.
组织细胞坏死性淋巴结炎或菊池-藤本病的特征是淋巴结炎症，其与系统性红斑狼疮的相似性已得到普遍认可。
我们对两例家族性病例的描述旨在提出这样一种假设，即效仿在自身免疫性疾病中观察到的情况，本病存在遗传背景。
菊池-藤本病的病理生理学可能是多因素的，可能包括易感性遗传背景以及可能的感染触发事件。
