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Oral antiviral therapy reduces the risk of hepatocellular carcinoma in persons with chronic hepatitis B infection: combining evidence and common sense.

作者信息

Kong Yuanyuan, You Hong, Jia Jidong

机构信息

Beijing Key Laboratory of Translational Medicine on Liver Cirrhosis, Clinical Epidemiology and EBM Unit and Liver Research Center, Beijing Friendship Hospital, National Clinical Research Center of Digestive Diseases, Capital Medical University, Beijing, 100050, People's Republic of China.

出版信息

Hepatol Int. 2016 Mar;10(2):239-41. doi: 10.1007/s12072-016-9714-9. Epub 2016 Feb 23.

DOI:10.1007/s12072-016-9714-9
PMID:26907706
Abstract
摘要

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Front Immunol. 2025 Jun 27;16:1603544. doi: 10.3389/fimmu.2025.1603544. eCollection 2025.
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本文引用的文献

1
Estimations of worldwide prevalence of chronic hepatitis B virus infection: a systematic review of data published between 1965 and 2013.全球慢性乙型肝炎病毒感染患病率的估计：1965 年至 2013 年发表数据的系统评价。
Lancet. 2015 Oct 17;386(10003):1546-55. doi: 10.1016/S0140-6736(15)61412-X. Epub 2015 Jul 28.
2
Effects of long-term entecavir treatment on the incidence of hepatocellular carcinoma in chronic hepatitis B patients.长期恩替卡韦治疗对慢性乙型肝炎患者肝细胞癌发生率的影响。
Hepatol Int. 2016 Mar;10(2):320-7. doi: 10.1007/s12072-015-9647-8. Epub 2015 Jul 22.
3
Hepatocellular carcinoma risk in chronic hepatitis B virus-infected compensated cirrhosis patients with low viral load.
慢性乙型肝炎病毒感染代偿性肝硬化患者低病毒载量与肝细胞癌风险。
Hepatology. 2015 Sep;62(3):694-701. doi: 10.1002/hep.27889. Epub 2015 Jul 3.
4
Significant reduction in end-stage liver diseases burden through the national viral hepatitis therapy program in Taiwan.通过台湾国家病毒性肝炎治疗计划显著降低终末期肝病负担。
Hepatology. 2015 Apr;61(4):1154-62. doi: 10.1002/hep.27630. Epub 2015 Feb 10.
5
Incidence of hepatocellular carcinoma after HBsAg seroclearance in chronic hepatitis B patients: a need for surveillance.HBsAg 血清学清除后慢性乙型肝炎患者肝细胞癌的发生率：需要进行监测。
J Hepatol. 2015 May;62(5):1092-9. doi: 10.1016/j.jhep.2014.11.031. Epub 2014 Nov 28.
6
The incidence of hepatocellular carcinoma is reduced in patients with chronic hepatitis B on long-term nucleos(t)ide analogue therapy.长期接受核苷（酸）类似物治疗的慢性乙型肝炎患者肝细胞癌的发病率降低。
Aliment Pharmacol Ther. 2014 Dec;40(11-12):1262-9. doi: 10.1111/apt.12990. Epub 2014 Oct 13.
7
Hepatocellular carcinoma risk in HBeAg-negative chronic hepatitis B patients with or without cirrhosis treated with entecavir: HepNet.Greece cohort.恩替卡韦治疗的HBeAg阴性慢性乙型肝炎患者（无论有无肝硬化）的肝细胞癌风险：希腊HepNet队列研究
J Viral Hepat. 2015 Feb;22(2):120-7. doi: 10.1111/jvh.12283. Epub 2014 Jul 15.
8
Entecavir treatment does not eliminate the risk of hepatocellular carcinoma in chronic hepatitis B: limited role for risk scores in Caucasians.恩替卡韦治疗不能消除慢性乙型肝炎患者肝细胞癌的风险：风险评分在白种人中作用有限。
Gut. 2015 Aug;64(8):1289-95. doi: 10.1136/gutjnl-2014-307023. Epub 2014 Jul 10.
9
Long term nucleotide and nucleoside analogs treatment in chronic hepatitis B HBeAg negative genotype D patients and risk for hepatocellular carcinoma.慢性乙型肝炎D基因型HBeAg阴性患者的长期核苷酸和核苷类似物治疗与肝细胞癌风险
Ann Hepatol. 2014 Jul-Aug;13(4):376-85.
10
Association of nucleos(t)ide analogue therapy with reduced risk of hepatocellular carcinoma in patients with chronic hepatitis B: a nationwide cohort study.核苷（酸）类似物治疗与慢性乙型肝炎患者肝细胞癌风险降低相关：一项全国性队列研究。
Gastroenterology. 2014 Jul;147(1):143-151.e5. doi: 10.1053/j.gastro.2014.03.048. Epub 2014 Apr 1.