Chantepie A, Colin A, David N, Iselin M, Lefèvre M
Service de pédiatrie A, Hôpital Clocheville, CHU Tours.
Arch Fr Pediatr. 1989 Nov;46(9):649-53.
A retrospective multicenter study was based on influential echocardiograms performed in 34 children, the majority (29/34) being under 2 years of age, and presenting with a primary form of acute congestive heart failure. Four died early. The average duration of serial echocardiographic monitoring was 25 months (9-72 months) in the others. During the acute stage, the left cardiac cavities were extremely dilated and the shortening fraction was reduced to 15 +/- 4%. The 4 decreased children belonged to a group of 17 children who had a shortening fraction less than 13%. From the 8th day significant improvement of the left ventricular function was observed. Recovery was faster during the first 6 months of evolution and became very low after 1 year. The age at onset, the severity of the initial left ventricular changes, and the speed of recovery during the first 15 days were not predictive of the degree of eventual recovery of left ventricular function. At the end of the study 28 of the 30 surviving children had recovered a normal shortening fraction. However 16 of 30 still showed some dilatation, albeit moderate in most cases, of this ventricle. These data show that most children presenting with a primary form of acute congestive heart failure recover satisfactory heart function and that the initial echocardiographic features are not predictive of the subsequent course.
一项回顾性多中心研究基于对34名儿童进行的有影响力的超声心动图检查,其中大多数(29/34)年龄在2岁以下,表现为原发性急性充血性心力衰竭。4例早期死亡。其他患儿连续超声心动图监测的平均时长为25个月(9 - 72个月)。急性期,心脏左腔极度扩张,缩短分数降至15±4%。4例病情恶化的儿童属于缩短分数低于13%的17名儿童组。从第8天开始观察到左心室功能有显著改善。在病程的前6个月恢复较快,1年后恢复速度变得非常缓慢。发病年龄、初始左心室改变的严重程度以及前15天的恢复速度均不能预测左心室功能最终的恢复程度。研究结束时,30名存活儿童中有28名恢复了正常的缩短分数。然而,30名儿童中有16名该心室仍有一定程度的扩张,尽管大多数情况下程度较轻。这些数据表明,大多数原发性急性充血性心力衰竭患儿恢复了令人满意的心脏功能,且初始超声心动图特征不能预测后续病程。