Saad Richard J
Division of Gastroenterology, University of Michigan Medical Center, 3912 Taubman Center, Ann Arbor, MI, USA.
Curr Gastroenterol Rep. 2016 Mar;18(3):14. doi: 10.1007/s11894-016-0489-x.
The wireless motility and pH capsule (WMC) provides an office-based test to simultaneously assess both regional and whole gut transit. Ingestion of this non-digestible capsule capable of measuring temperature, pH, and the pressure of its immediate surroundings allows for the measurement of gastric, small bowel, and colonic transit times in an ambulatory setting. Approved by the US Food and Drug Administration for the evaluation of suspected conditions of delayed gastric emptying and the evaluation of colonic transit in chronic idiopathic constipation, WMC should be considered in suspected gastrointestinal motility disorders as it provides a single study capable of simultaneously assessing for regional, multiregional, or generalized motility disorders. Specific indications for testing with the WMC should include the evaluation of suspect cases of gastroparesis, small bowel dysmotility, and slow transit constipation, as well as symptom syndromes suggestive of a multiregional or generalized gastrointestinal transit delay.
无线动力和pH胶囊(WMC)提供了一种基于门诊的测试,可同时评估局部和全肠道转运情况。摄入这种能够测量温度、pH值及其周围环境压力的不可消化胶囊,可在动态环境中测量胃、小肠和结肠的转运时间。WMC已获得美国食品药品监督管理局批准,用于评估疑似胃排空延迟情况以及慢性特发性便秘患者的结肠转运情况。对于疑似胃肠动力障碍患者,应考虑使用WMC,因为它能通过一项研究同时评估局部、多区域或全身性动力障碍。使用WMC进行测试的具体指征应包括评估疑似胃轻瘫、小肠动力障碍和慢传输型便秘的病例,以及提示多区域或全身性胃肠转运延迟的症状综合征。