应用无线动力胶囊来测定危重症创伤患者的胃排空和小肠传输时间。
Use of wireless motility capsule to determine gastric emptying and small intestinal transit times in critically ill trauma patients.
机构信息
Department of Anesthesiology, University of Würzburg, Germany.
出版信息
J Crit Care. 2012 Oct;27(5):534.e7-12. doi: 10.1016/j.jcrc.2011.12.002. Epub 2012 Feb 1.
PURPOSE
The purpose of this study is to use a novel wireless motility capsule to compare gastric emptying and small bowel transit times in critically ill trauma patients and healthy volunteers.
MATERIALS AND METHODS
We evaluated gastric emptying, small bowel transit time, and total intestinal transit time in 8 critically ill trauma patients. These data were compared with those obtained in 87 healthy volunteers from a separate trial. Data were obtained with a motility capsule that wirelessly transmitted pH, pressure, and temperature to a recorder attached to each subject's abdomen.
RESULTS
The gastric emptying time was significantly longer in critically ill patients (median, 13.9; interquartile range [IQR], 6.6-48.3 hours) than in healthy volunteers (median, 3.0; IQR, 2.5-3.9 hours), P < .001. The small bowel transit time in critically ill patients was significantly longer than in healthy volunteers (median, 6.7 hours; IQR, 4.4-8.5 hours vs median, 3.8 hours; IQR, 3.1-4.7 hours), P = .01. Furthermore, the capsules passed after 10 (IQR, 8.5-13) days in the critical care group and 1.2 (IQR, 0.9-1.9) days in healthy volunteers (P < .001).
CONCLUSIONS
Both gastric emptying and small bowel transit were delayed in critically ill trauma patients.
目的
本研究旨在使用新型无线动力胶囊比较危重症创伤患者和健康志愿者的胃排空和小肠转运时间。
材料和方法
我们评估了 8 例危重症创伤患者的胃排空、小肠转运时间和总肠转运时间。这些数据与来自另一项试验的 87 例健康志愿者的数据进行了比较。数据是通过一个无线传输 pH 值、压力和温度到每个受试者腹部附着的记录仪的动力胶囊获得的。
结果
危重症患者的胃排空时间明显长于健康志愿者（中位数 13.9；四分位距 [IQR]，6.6-48.3 小时），P<0.001。危重症患者的小肠转运时间明显长于健康志愿者（中位数 6.7 小时；IQR，4.4-8.5 小时 vs 中位数 3.8 小时；IQR，3.1-4.7 小时），P=0.01。此外，在重症监护组中，胶囊在 10 天后（IQR，8.5-13）通过，而在健康志愿者中为 1.2 天（IQR，0.9-1.9）（P<0.001）。
结论
危重症创伤患者的胃排空和小肠转运均延迟。
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