Department of Anesthesiology, University of Würzburg, Germany.
J Crit Care. 2012 Oct;27(5):534.e7-12. doi: 10.1016/j.jcrc.2011.12.002. Epub 2012 Feb 1.
The purpose of this study is to use a novel wireless motility capsule to compare gastric emptying and small bowel transit times in critically ill trauma patients and healthy volunteers.
We evaluated gastric emptying, small bowel transit time, and total intestinal transit time in 8 critically ill trauma patients. These data were compared with those obtained in 87 healthy volunteers from a separate trial. Data were obtained with a motility capsule that wirelessly transmitted pH, pressure, and temperature to a recorder attached to each subject's abdomen.
The gastric emptying time was significantly longer in critically ill patients (median, 13.9; interquartile range [IQR], 6.6-48.3 hours) than in healthy volunteers (median, 3.0; IQR, 2.5-3.9 hours), P < .001. The small bowel transit time in critically ill patients was significantly longer than in healthy volunteers (median, 6.7 hours; IQR, 4.4-8.5 hours vs median, 3.8 hours; IQR, 3.1-4.7 hours), P = .01. Furthermore, the capsules passed after 10 (IQR, 8.5-13) days in the critical care group and 1.2 (IQR, 0.9-1.9) days in healthy volunteers (P < .001).
Both gastric emptying and small bowel transit were delayed in critically ill trauma patients.
本研究旨在使用新型无线动力胶囊比较危重症创伤患者和健康志愿者的胃排空和小肠转运时间。
我们评估了 8 例危重症创伤患者的胃排空、小肠转运时间和总肠转运时间。这些数据与来自另一项试验的 87 例健康志愿者的数据进行了比较。数据是通过一个无线传输 pH 值、压力和温度到每个受试者腹部附着的记录仪的动力胶囊获得的。
危重症患者的胃排空时间明显长于健康志愿者（中位数 13.9；四分位距 [IQR]，6.6-48.3 小时），P<0.001。危重症患者的小肠转运时间明显长于健康志愿者（中位数 6.7 小时；IQR，4.4-8.5 小时 vs 中位数 3.8 小时；IQR，3.1-4.7 小时），P=0.01。此外，在重症监护组中，胶囊在 10 天后（IQR，8.5-13）通过，而在健康志愿者中为 1.2 天（IQR，0.9-1.9）（P<0.001）。
危重症创伤患者的胃排空和小肠转运均延迟。
