解剖学德凯评分与成人喉乳头状瘤病的嗓音障碍相关。
Anatomic Derkay Score Is Associated with Voice Handicap in Laryngeal Papillomatosis in Adults.
作者信息
Kupfer Robbi A, Çadalli Tatar Emel, Barry Jonnae O, Allen Clint T, Merati Albert L
机构信息
Department of Otolaryngology-Head and Neck Surgery, University of Washington School of Medicine, Seattle, Washington, USA Department of Otolaryngology-Head and Neck Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA
Department of Otolaryngology-Head and Neck Surgery, University of Washington School of Medicine, Seattle, Washington, USA Department of Otolaryngology, Dişkapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey.
出版信息
Otolaryngol Head Neck Surg. 2016 Apr;154(4):689-92. doi: 10.1177/0194599816628871. Epub 2016 Feb 23.
OBJECTIVE
The Derkay staging system quantifies recurrent respiratory papillomatosis (RRP) severity based on involvement of laryngeal structures. Despite its broad use in the laryngology literature, the association between Derkay score and voice-related quality of life has not previously been studied. It is hypothesized that Derkay score positively correlates with the Voice Handicap Index-10 (VHI-10).
STUDY DESIGN
Case series with chart review.
SETTING
Tertiary medical center.
SUBJECTS AND METHODS
Forty-six adult RRP patients treated from 2007 to 2013 at a tertiary medical center were included. Anatomic Derkay scores at the time of each RRP procedure were calculated. VHI-10 scores obtained within 30 days preceding the procedures were used to assess for correlation between Derkay staging system and VHI-10.
RESULTS
Ninety-three procedures performed on 46 patients met inclusion criteria. Mean Derkay score was 11.9 (range, 2-28), and mean VHI-10 was 18.0 (range, 0-40). There was a significant positive correlation between Derkay score and VHI-10 (Spearman coefficient r = 0.42, P < .0001).
CONCLUSION
The anatomic burden of RRP as assessed by Derkay staging system is positively correlated with voice-related quality of life as quantified by the VHI-10.
目的
德凯分期系统根据喉结构受累情况对复发性呼吸道乳头状瘤病（RRP）的严重程度进行量化。尽管该系统在喉科学文献中被广泛应用，但此前尚未对德凯评分与嗓音相关生活质量之间的关联进行研究。研究假设德凯评分与嗓音障碍指数-10（VHI-10）呈正相关。
研究设计
病例系列研究并进行病历回顾。
研究地点
三级医疗中心。
研究对象与方法
纳入2007年至2013年在一家三级医疗中心接受治疗的46例成年RRP患者。计算每次RRP手术时的解剖学德凯评分。使用手术前30天内获得的VHI-10评分来评估德凯分期系统与VHI-10之间的相关性。
结果
对46例患者实施的93例手术符合纳入标准。德凯评分的平均值为11.9（范围为2 - 28），VHI-10的平均值为18.0（范围为0 - 40）。德凯评分与VHI-10之间存在显著正相关（斯皮尔曼系数r = 0.42，P <.0001）。
结论
德凯分期系统评估的RRP解剖学负担与VHI-10量化的嗓音相关生活质量呈正相关。
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