Massari Francesco, Henninger Nils, Lozano Juan Diego, Patel Anand, Kuhn Anna Luisa, Howk Mary, Perras Mary, Brooks Christopher, Gounis Matthew J, Kan Peter, Wakhloo Ajay K, Puri Ajit S
Division Neuroimaging and Intervention (NII) and New England Center for Stroke Research, Department of Radiology, University of Massachusetts, Worcester, USA
Departments of Neurology and Psychiatry, University of Massachusetts, Worcester, USA.
Interv Neuroradiol. 2016 Jun;22(3):325-32. doi: 10.1177/1591019916632369. Epub 2016 Feb 22.
A new generation of highly navigable large-bore aspiration catheters and retriever devices for intracranial mechanical thrombectomy has markedly improved recanalization rates, time and clinical outcomes. We report collected clinical data utilizing a new technique based on combined large lumen aspiration catheter and partially resheathed stent retriever (ARTS: Aspiration (catheter)-(stent) Retriever Technique for Stroke). This technique is applied, especially in presence of bulky/rubbery emboli, when resistance is felt while retracting the stent retriever; at that point the entire assembly is locked and removed in-toto under continuous aspiration with additional flow arrest.
A retrospective data analysis was performed to identify patients with large cerebral artery acute ischemic stroke treated with ARTS. The study was conducted between August 2013 and February 2015 at a single high volume stroke center. Procedural and clinical data were captured for analysis.
Forty-two patients (median age 66 years) met inclusion criteria for this study. The ARTS was successful in achieving Thrombolysis in Cerebral Infarction (TICI) ≥2b revascularization in 97.6% of cases (TICI 2b = 18 patients, TICI 3 = 23 patients). Patients' median National Institutes of Health Stroke Scale score at admission was 18 (6-40). A 3-month follow-up modified Rankin Scale value of 0-2 was achieved in 65.7% of the successfully treated patients (average 2.4). Two patients (4.8%) developed symptomatic intraparenchymal hemorrhages. Six procedure unrelated deaths were observed.
We found that ARTS is a fast, safe and effective method for endovascular recanalization of large vessel occlusions presenting within the context of acute ischemic stroke.
新一代用于颅内机械取栓的高可导航性大口径抽吸导管和回收装置显著提高了再通率、缩短了时间并改善了临床结局。我们报告了利用一种基于联合大腔抽吸导管和部分重新鞘管化的支架回收器(ARTS:用于卒中的抽吸(导管)-(支架)回收技术)的新技术收集的临床数据。该技术尤其适用于存在体积较大/质地较软的栓子、在回撤支架回收器时感觉到阻力的情况;此时,在持续抽吸并额外实现血流阻断的情况下,将整个组件锁定并整体取出。
进行回顾性数据分析,以确定接受ARTS治疗的大脑中动脉急性缺血性卒中患者。该研究于2013年8月至2015年2月在一个高容量卒中中心进行。收集手术和临床数据进行分析。
42例患者(中位年龄66岁)符合本研究的纳入标准。ARTS在97.6%的病例中成功实现了脑梗死溶栓(TICI)≥2b级再通(TICI 2b = 18例患者,TICI 3 = 23例患者)。患者入院时美国国立卫生研究院卒中量表评分的中位数为18(6 - 40)。在65.7%成功治疗的患者中,3个月随访时改良Rankin量表评分为0 - 2(平均2.4)。2例患者(4.8%)发生有症状的脑实质内出血。观察到6例与手术无关的死亡。
我们发现ARTS是一种快速、安全且有效的方法,用于急性缺血性卒中背景下大血管闭塞的血管内再通。