阿可乐定在前节激光手术患者中的疗效与安全性。
Efficacy and safety of apraclonidine in patients undergoing anterior segment laser surgery.
作者信息
Sridharrao B, Badrinath S S
机构信息
Vision Research Foundation, Madras, India.
出版信息
Br J Ophthalmol. 1989 Nov;73(11):884-7. doi: 10.1136/bjo.73.11.884.
Abstract
The efficacy of 1.0% apraclonidine (para-aminoclonidine) in preventing the rise of intraocular pressure following anterior segment, laser surgery was evaluated in a randomised double-masked study. Ninety-nine consecutive patients requiring laser treatment of the anterior segment were included in the study. They were randomised into two groups, one receiving 1.0% para-aminoclonidine and the other placebo (vehicle of para-aminoclonidine). The drug caused a statistically significant reduction in pressure after the laser treatment without causing clinically significant side effects such as bradycardia or hypotension.
摘要
在一项随机双盲研究中，评估了1.0%阿可乐定（对氨基可乐定）预防眼前节激光手术后眼压升高的疗效。该研究纳入了99例连续需要进行眼前节激光治疗的患者。他们被随机分为两组，一组接受1.0%对氨基可乐定，另一组接受安慰剂（对氨基可乐定的赋形剂）。该药物在激光治疗后使眼压有统计学意义的降低，且未引起如心动过缓或低血压等具有临床意义的副作用。
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本文引用的文献
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Immediate intraocular pressure response to argon laser trabeculoplasty.
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Neodymium-YAG laser for posterior capsulotomy.用于后囊切开术的钕钇铝石榴石激光。
Am J Ophthalmol. 1983 Dec;96(6):716-20. doi: 10.1016/s0002-9394(14)71912-9.
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The immediate IOP response of Nd-YAG-laser iridotomy and its prophylactic treatability.钕钇铝石榴石激光虹膜切开术的即时眼压反应及其预防性治疗效果。
Acta Ophthalmol (Copenh). 1984 Oct;62(5):673-80. doi: 10.1111/j.1755-3768.1984.tb05794.x.
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A comparison of neodymium: YAG and argon laser iridotomies.钕:钇铝石榴石激光与氩激光虹膜切开术的比较。
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