Schrems W, Eichelbrönner O, Krieglstein G K
Acta Ophthalmol (Copenh). 1984 Oct;62(5):673-80. doi: 10.1111/j.1755-3768.1984.tb05794.x.
The response of IOP in the normotensive human eye to Neodym-YAG-laser iridotomy was investigated in this study. In 2 series of 10 patients, each unilateral laser iridotomy was performed with a YAG-laser prior to cataract surgery. In one group laser iridotomy was done without pre-treatment, in the second group laser iridotomy was preceded by treatment with 1% pilocarpine. Close follow-up of IOP before and after surgery was carried out with the Non-Contact-Tonometer. Laser iridotomy caused average IOP rises of 10 mmHg, which could be identified as early as 20 min after surgery, with a maximum of response after 80 min, and a declining IOP from 100 min post-operatively onwards. Pre-treatment with pilocarpine eyedrops could be reduce the laser-mediated IOP rise to less than one fourth. These results recommend a mild miotic for routine pre-treatment for iris laser surgery in order to cope with acute pressure rise as one of the major problems in these procedures.
本研究调查了正常眼压人眼对钕钇铝石榴石激光虹膜切开术的眼压反应。在两组各10例患者中，每例均在白内障手术前用钕钇铝石榴石激光进行单侧激光虹膜切开术。一组在未进行预处理的情况下进行激光虹膜切开术，另一组在激光虹膜切开术前用1%毛果芸香碱治疗。使用非接触眼压计对手术前后的眼压进行密切随访。激光虹膜切开术导致眼压平均升高10 mmHg，术后20分钟即可发现，术后80分钟反应最大，术后100分钟起眼压下降。术前用毛果芸香碱滴眼液治疗可将激光介导的眼压升高降低至不到四分之一。这些结果建议在虹膜激光手术常规预处理中使用轻度缩瞳剂，以应对这些手术中的主要问题之一——急性眼压升高。
