Oh Phil-Sun, Hwang Hyosook, Jeong Hwan-Seok, Kwon Jeongil, Kim Hyun-Soo, Kim Minjoo, Lim SeokTae, Sohn Myung-Hee, Jeong Hwan-Jeong
Department of Nuclear Medicine, Molecular Imaging & Therapeutic Medicine Research Center, Cyclotron Research Center, Institute for Medical Sciences, Biomedical Research Institute, Chonbuk National University Medical School and Hospital, Jeonju, Jeonbuk 561-712, Republic of Korea.
Data Brief. 2016 Jan 15;6:630-3. doi: 10.1016/j.dib.2016.01.018. eCollection 2016 Mar.
As a new and preferred light source for phototherapy, blue light emitting diodes (LEDs) with wavelengths of 400-500 nm have been used to treat hyperbilirubinaemia in infantile jaundice [1]. Recent studies report that blue LED irradiation induces apoptosis by stimulating a mitochondrial pathway and reduces the early growth rate of melanoma cells in mice [2]. Here, we detected the induction of apoptotic cell death and formation of autophagosome in human B lymphoma cells after irradiation with blue LED. This paper provides data in support of the research article entitled "Blue light emitting diode induces apoptosis in lymphoid cells by stimulating autophagy" [3].
作为光疗的一种新型且首选光源，波长为400 - 500纳米的蓝光发光二极管（LED）已被用于治疗婴儿黄疸中的高胆红素血症[1]。最近的研究报告称，蓝光LED照射通过刺激线粒体途径诱导细胞凋亡，并降低小鼠黑色素瘤细胞的早期生长速率[2]。在此，我们检测了蓝光LED照射后人B淋巴瘤细胞中凋亡性细胞死亡的诱导情况以及自噬体的形成。本文提供的数据支持了题为“蓝光发光二极管通过刺激自噬诱导淋巴细胞凋亡”的研究文章[3]。
