Saiapina O Y, Kharchenko S G, Vishnevskii S G, Pyeshkova V M, Kalchenko V I, Dzyadevych S V
Laboratory of Biomolecular Electronics, Institute of Molecular Biology and Genetics of National Academy of Sciences of Ukraine, 150 Zabolotnogo Str., 03680, Kyiv, Ukraine.
Institute of Organic Chemistry of National Academy of Sciences of Ukraine, 5 Murmanska Str., 02660, Kyiv, Ukraine.
Nanoscale Res Lett. 2016 Dec;11(1):105. doi: 10.1186/s11671-016-1317-9. Epub 2016 Feb 25.
The conductometric sensor based on 25,27-di-(5-thio-octyloxy)calix[4]arene-crown-6 was developed for the quantitative analysis of ammonium. The calixarene was immobilized on the surface of the planar interdigitated electrodes by attachment of its dialkyl sulfide groups to the surface of the gold electrodes. The intrinsic ability of the calixarene to capture ammonium was studied in the conductometric measuring mode and by the electrochemical impedance spectroscopy. The developed sensor showed high selectivity to ammonium in the presence of mono-, di-, and trivalent cations. Selective and highly sensitive detection of ammonium resulted from the complexation between the ammonium ions and a crown-ether fragment of the upper rim of the 25,27-di-(5-thio-octyloxy)calix[4]arene-crown-6 macrocycle. The developed sensor had high signal repeatability. Its sensitivity was found to be satisfactory for the forthcoming sensor application in the water-sample analysis; the linear range was 0.01-1.5 mM and limit of detection 10 μM.
基于25,27-二（5-硫代辛氧基）杯[4]芳烃-冠-6的电导传感器被开发用于铵的定量分析。杯芳烃通过其二烷基硫醚基团附着在金电极表面而固定在平面叉指电极表面。在电导测量模式和电化学阻抗谱中研究了杯芳烃捕获铵的内在能力。所开发的传感器在一价、二价和三价阳离子存在下对铵具有高选择性。铵离子与25,27-二（5-硫代辛氧基）杯[4]芳烃-冠-6大环上缘的冠醚片段之间的络合导致了对铵的选择性和高灵敏度检测。所开发的传感器具有高信号重复性。发现其灵敏度对于即将在水样分析中应用的传感器来说是令人满意的；线性范围为0.01-1.5 mM，检测限为10 μM。
