Addadi L, Berman A, Oldak J M, Weiner S
Dept. Structural Chemistry, Weizmann Institute of Science.
Connect Tissue Res. 1989;21(1-4):127-34; discussion 135. doi: 10.3109/03008208909050003.
Detailed studies of the molecular organization of various mineralized tissues highlight the role played by acidic glycoproteins in controlling crystal formation. In vitro experiments show that these macromolecules are able to interact with specific faces of different crystals, influencing both nucleation and crystal growth. Significantly a common stereochemical motif can be recognized in all the interacting faces studies to date.
对各种矿化组织分子结构的详细研究突出了酸性糖蛋白在控制晶体形成中所起的作用。体外实验表明,这些大分子能够与不同晶体的特定晶面相互作用,影响成核和晶体生长。值得注意的是,在迄今为止所有研究的相互作用晶面中都能识别出一个共同的立体化学基序。