酸性蛋白质与晶体之间的相互作用：生物矿化中的立体化学要求。

Proc Natl Acad Sci U S A. 1985 Jun;82(12):4110-4. doi: 10.1073/pnas.82.12.4110.

Acidic matrix macromolecules are intimately involved in biological crystal growth. In vitro experiments, in which crystals of calcium dicarboxylate salts were grown in the presence of aspartic acid-rich proteins, revealed a stereochemical property common to all the interacting faces. Calcite crystals are nucleated on stereochemically analogous faces when proteins are adsorbed onto a rigid substrate. The importance of this property in biomineralization is discussed.

酸性基质大分子与生物晶体生长密切相关。在体外实验中，在富含天冬氨酸的蛋白质存在的情况下生长二羧酸盐晶体，揭示了所有相互作用面共有的立体化学性质。当蛋白质吸附到刚性基质上时，方解石晶体在立体化学上类似的面上成核。讨论了这种性质在生物矿化中的重要性。