Ulcerative colitis in a patient with common variable immunodeficiency: does the treatment differ from the routine?

Common variable immunodeficiency (CVID) is associated with gastrointestinal manifestations, in particular diarrhea (1,2). It is linked to autoimmune disorders such as nodular lymphoid hyperplasia (NLH), possibly increasing the risk of lymphoma (3). The prevalence of chronic inflammatory bowel disease (CIBD) in these patients is increased, above all Crohn's disease (4,5) and its treatment does not seem to differ from the standard (2). We were presented with a patient with CVID and ulcerative colitis treated in the conventional manner.