2型糖尿病中的睡眠呼吸暂停
Sleep Apnea in Type 2 Diabetes.
作者信息
Doumit Jimmy, Prasad Bharati
机构信息
Jesse Brown VA Medical Center and University of Illinois at Chicago, Chicago, IL.
出版信息
Diabetes Spectr. 2016 Feb;29(1):14-9. doi: 10.2337/diaspect.29.1.14.
Abstract
IN BRIEF Obstructive sleep apnea (OSA) alters glucose metabolism, promotes insulin resistance, and is associated with development of type 2 diabetes. Obesity is a key moderator of the effect of OSA on type 2 diabetes. However, chronic exposure to intermittent hypoxia and other pathophysiological effects of OSA affect glucose metabolism directly, and treatment of OSA can improve glucose homeostasis.
摘要
简而言之，阻塞性睡眠呼吸暂停（OSA）会改变葡萄糖代谢，促进胰岛素抵抗，并与2型糖尿病的发生有关。肥胖是OSA对2型糖尿病影响的关键调节因素。然而，长期暴露于间歇性缺氧及OSA的其他病理生理效应会直接影响葡萄糖代谢，而OSA的治疗可改善葡萄糖稳态。
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