Hong Su Jin, Yoon Dae Young, Cho Young Kwon, Yoon Soo Jeong, Moon Ji Yoon, Baek Sora, Lim Kyoung Ja
1 All authors: Department of Radiology, Kangdong Seong-Sim Hospital, Hallym University College of Medicine, 150, Seongan-Ro Gangdong-Gu, Seoul 134-701, Korea.
AJR Am J Roentgenol. 2016 May;206(5):917-23. doi: 10.2214/AJR.15.15640. Epub 2016 Feb 25.
The aim of this bibliometric study was to assess the characteristics and quality of radiologic randomized controlled trials (RCTs) over the past 20 years.
A PubMed search was conducted to identify radiologic RCTs (defined as RCTs in which the first author or corresponding author is affiliated with a radiology department) published between 1995 and 2014. The following information was extracted from each article: journal, radiologic subspecialty, imaging technique, number of subjects, study result, funding, number of authors, number of institutions, country of origin, and methodologic quality (assessed using the Jadad scale).
A total of 358 radiologic RCTs were published between 1995 and 2014. Dramatic increases in the numbers of radiologic RCTs were found, from 43 conducted in 1995-1999 to 172 conducted in 2010-2014. One-hundred seventeen (32.7%) RCTs were concerned with the field of vascular and interventional radiology; 78 (21.8%) evaluated more than one imaging technique; 164 (45.8%) had a sample size of 50-150 subjects; 246 (68.7%) showed positive study results; 185 (51.7%) were not funded; 179 (50.0%) had four to seven authors; 263 (73.5%) were single-center trials; 88 (24.6%) had a first author or corresponding author located in the United States; and 187 (52.2%) were of low quality. In the time trend analysis, the following variables showed a significantly positive trend: abdominal imaging subspecialty, CT as the imaging technique, more than 150 subjects, more than seven authors, and high methodologic quality.
The quantity and quality of radiologic RCTs have significantly increased over the past 2 decades; however, the methodologic quality remains suboptimal.
本文献计量学研究旨在评估过去20年放射学随机对照试验（RCT）的特征和质量。
通过PubMed检索，以识别1995年至2014年间发表的放射学RCT（定义为第一作者或通讯作者隶属于放射科的RCT）。从每篇文章中提取以下信息：期刊、放射学亚专业、成像技术、受试者数量、研究结果、资金、作者数量、机构数量、原产国以及方法学质量（使用Jadad量表评估）。
1995年至2014年间共发表了358项放射学RCT。发现放射学RCT的数量显著增加，从1995 - 1999年进行的43项增加到2010 - 2014年进行的172项。117项（32.7%）RCT涉及血管与介入放射学领域；78项（21.8%）评估了不止一种成像技术；164项（45.8%）的样本量为50 - 150名受试者；246项（68.7%）显示出阳性研究结果；185项（51.7%）未获得资金支持；179项（50.0%）有四至七名作者；263项（73.5%）为单中心试验；88项（24.6%）的第一作者或通讯作者位于美国；187项（52.2%）质量较低。在时间趋势分析中，以下变量呈现出显著的正趋势：腹部成像亚专业、CT作为成像技术、超过150名受试者、超过七名作者以及高方法学质量。
在过去20年中，放射学RCT的数量和质量显著增加；然而，方法学质量仍不理想。
