22q11.2缺失综合征青少年的多任务处理能力：来自实验性生态范式的结果
Multitasking Abilities in Adolescents With 22q11.2 Deletion Syndrome: Results From an Experimental Ecological Paradigm.
作者信息
Schneider Maude, Eliez Stephan, Birr Julie, Menghetti Sarah, Debbané Martin, Van der Linden Martial
机构信息
Maude Schneider, Office Médico-Pédagogique Research Unit, Department of Psychiatry, School of Medicine, and Cognitive Psychopathology, and Neuropsychology Unit, Faculty of Psychology and Educational Sciences, University of Geneva, Geneva, Switzerland;
Stephan Eliez, Office Médico-Pédagogique Research Unit, Department of Psychiatry, and Department of Genetic Medicine and Development, School of Medicine, University of Geneva, Geneva, Switzerland;
出版信息
Am J Intellect Dev Disabil. 2016 Mar;121(2):151-64. doi: 10.1352/1944-7558-121.2.151.
The 22q11.2 deletion syndrome (22q11.2DS) is associated with cognitive and functional impairments and increased risk for schizophrenia. We characterized multitasking abilities of adolescents with 22q11.2DS using an experimental naturalistic setting and examined whether multitasking impairments were associated with real-world functioning and negative symptoms. Thirty-nine adolescents (19 with 22q11.2DS and 20 controls) underwent the Multitasking Evaluation for Adolescents. Real-world functioning and clinical symptoms were assessed in participants with 22q11.2DS. Adolescents with 22q11.2DS performed poorly in the multitasking evaluation. Our data also suggest that multitasking abilities are related to adaptive functioning in the practical domain and negative symptoms. This study shows that adolescents with 22q11.2DS are characterized by multitasking impairments, which may be relevant for several aspects of the clinical phenotype.
22q11.2缺失综合征（22q11.2DS）与认知和功能障碍以及精神分裂症风险增加有关。我们使用实验性自然情境对患有22q11.2DS的青少年的多任务处理能力进行了特征描述，并研究了多任务处理障碍是否与现实世界功能和阴性症状相关。39名青少年（19名患有22q11.2DS，20名作为对照）接受了青少年多任务评估。对患有22q11.2DS的参与者的现实世界功能和临床症状进行了评估。患有22q11.2DS的青少年在多任务评估中表现不佳。我们的数据还表明，多任务处理能力与实际领域的适应性功能和阴性症状有关。这项研究表明，患有22q11.2DS的青少年具有多任务处理障碍的特征，这可能与临床表型的几个方面相关。
Zotero 插件